Sinomenine hydrochloride ufa
Sinomenine hydrochloride ndi mankhwala ophatikizika kuchokera ku chomera Simomenium Acutum, omwe amapezeka ku East Asia. Ndi ma alkaloid omwe kale amagwiritsidwa ntchito mwamwambo mankhwala a Chinese mankhwala a anti-yotupa ndi analgesic katundu. Fomu ya hydrochloride ndi mchere womwe umawonjezera kusungunuka ndi kukhazikika, kumapangitsa kuti zikhale zoyenera kugwiritsa ntchito mankhwala.
Sinomenine hydrochloride adaphunziridwa chifukwa cha zochizira zomwe zingakhale zochizira pochiza zinthu monga nyamakazi, chifukwa kuthekera kwake kusinthira chitetezo cha mthupi ndikuchepetsa kutupa. Imagwira poletsa kupanga ma cytokines ofiyira komanso ofalitsa mabuku ena omwe amakhudzidwa ndi kutupa.
Kuphatikiza pa anti-kutupa kwake komanso analgemic zotsatira, sinomenine hydrochloride yawonetsanso kuthekera kwa neurophtection, anti-fibrosis, ndi chotupa choluka m'maphunziro osiyanasiyana.
Dzina la dzina: (9a, 13a) -7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-monohydrochloride
Nambala ya Cas: 6080-7
Synonyms: Cucoline NSC 76021
Ma molecular fomula: c19h23no4 • hcl
Formula Wild: 365.9
Kuyera: ≥98% Crystalline
Kusungunuka (phunzirani za kusiyanasiyana ku Solubility)
DMF: 30 mg / ml
DMSO: 30 mg / ml
Ethanol: 5 mg / ml
Pbs (PH 7.2): 5 mg / ml
Choyambira: Zomera / Sinomenuum Acutum
Kutumiza & Kusunga:
Kusunga -20 ° C
Kutumiza: kutentha kwa chipinda
Kukhazikika: ≥ 4 zaka
Chinthu | Chifanizo | Malipiro |
Gawani (HPLC) | 98.0% | 98.12% |
Kaonekedwe | ufa woyera | Zikugwirizana |
Kukula kwa tinthu | 98% kudutsa 80mesh | Zikugwirizana |
Fungo | Khalidwe | Zikugwirizana |
Kakomedwe | Khalidwe | Zikugwirizana |
Makhalidwe Athupi | ||
Kutayika pakuyanika | ≤0.5% | 0.38% |
Phulusa | ≤0.5% | 0.46% |
Zitsulo Zolemera | ||
Zitsulo zolemera (monga PB) | Malangizo a USP (<10ppm) | <10ppm |
Arsenic (monga) | ≤2pmm | 0.78PPM |
Atsogolera (PB) | ≤2pmm | 1.13ppm |
Cadmium (CD) | ≤lppm | 0.36ppm |
Mercarry (hg) | ≤0.1PPM | 0.000Pm |
Zotsalira za Mastistide | Osapezeka | Osapezeka |
Chiwerengero chonse | Nmt 10000cfu / g | 680 cfu / g |
Yisiti ndi nkhungu | Nmt 100cfu / g | 87 CFU / g |
E.coli | Nmt 30cfu / g | 10 cfu / g |
Nsomba monomolla | Wosavomela | Wosavomela |
Mapeto | Kugwirizana ndi Muyeso wa Enterprise |
Zotsatira zazikulu za Sinomenine hydrochloride ndi:
(1) anti-yotupa: amachepetsa kutupa.
(2) analgesic: Amapereka zowawa.
(3) Immunosuppresve: imaletsa zochitika za mthupi.
(4) Anti-Rheumatic: amachita nyamakazi ya rheumatoid.
(5) neuroprotective: Amateteza maselo amitsempha kuti asawonongeke.
(6) Anti-fibrotic: amalepheretsa kapena amachepetsa minofu fibrosis.
Sinomenine hydrochloride amagwiritsidwa ntchito makamaka m'magawo otsatirawa:
(1) Rheumatogy: Chithandizo cha nyamakazi ya rheumatoid.
(2) Madandaulo a ululu: Kuthekera kwa ululu waukulu.
(3) Anti-yotupa: Kuchepetsa kwa kutupa.
(4) Kusauka: Kusintha kwa chitetezo cha mthupi.
(5) neurophtection: Kugwiritsa ntchito m'mayeso a mitsempha.
Kupanga kwa Sinomenine hydrochloride ufa kumatha kufupikitsidwa motere:
Kukonzekera kwa Herb:Kuyeretsa ndi kuyanika zomera zaiwisi.
Kuchotsa:Kugwiritsa ntchito sol solts ngati ethanol kuti atulutse Sinomenine ku chomera.
Kuzemba:Kusinthanitsa kosungunulira kuti amveke bwino zazomwe zilimo.
Alkirization:Kusintha pH kuti isinthe sichichimo ndi mchere.
Madzimadzi amadzimadzi:Kutsuka ndi ma soric sol ngati chisono kapena 1-heptanol.
Kuchapa:Kusamba kwamadzi kuti muchotse zodetsa ndi zosungunulira.
Acidination:Kuchepetsa PH kuti muchepetse sinomenine hydrochloride.
Crystallization:Kupanga makristali a sinomenine hydrochloride.
Kupatukana:Mitundu ya centerrifing kapena kusefa kuti alekanitse makhiristo ku yankho.
Kuyanika:Kuchotsa chinyezi chotsalira kuchokera ku makhiristo.
Kuthera:Kupera makhiristo owuma kukhala ufa wabwino.
Kuyimba:Kuonetsetsa kugawa kofanana ndi tinthu tambiri.
Kuwongolera kwapadera:Kuyesedwa kwa kuyera, kukhazikika, ndi mikhalidwe yazikhalidwe zachikhalidwe.
Kuyika:Kuyika mosatekeseka kuti agawidwe.
Kusungidwa: Khalani pamalo ozizira, owuma, komanso oyera, kuteteza ku chinyezi komanso kuwala.
Phukusi la Bisi: 25kg / Drum.
Nthawi Yotsogola: Patatha masiku 7 mutayitanitsa.
Moyo wa alumali: zaka 2.
Dzukani: Zida zamakono zitha kupezekanso.

Lankhula
Pansi pa 100kg, 3-5days
Khomo lolowera chitseko chosavuta kunyamula katundu
Mwa nyanja
Onjezerani300kg, pafupifupi masiku 30
Port to Port Services Claker Claker yofunika
Ndi mpweya
100kg-1000kg, 5-7days
Airport kupita ku Airport Service Service Claker Claker yofunika

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