Vinca Rosea Extract Vincristine

Chiyambi cha Latin:Catharanthus roseus (L.) G. Don,
Mayina Ena:Vinca Rosea;Madagascar periwinkle;Rosy periwinkle;Vinca;Old Maid;Cape periwinkle;Rose periwinkle;
Katundu Wazinthu:Vincristine> 98%
Mulingo Wotulutsa:4:1–20:1
Zomwe Zimagwira:Vincristine
Maonekedwe:White Crystalline Powder
Chomera Chogwiritsidwa Ntchito:Maluwa
Yankho la Extract:Madzi/Ethanol
Mbali:Anti-khancer, Kusokoneza kukula kwa maselo a khansa

 


Tsatanetsatane wa Zamalonda

Zina Zambiri

Zolemba Zamalonda

Chiyambi cha Zamalonda

Vinca Rosea Extract Vincristine amatanthauza mankhwala a Vincristine, omwe amachokera ku chomera cha periwinkle (Vinca rosea), chomwe chimadziwikanso kuti Catharanthus roseus, maso owala, Cape periwinkle, chomera chamanda, Madagascar periwinkle, mdzakazi wakale, pinki periwinkle, rose. periwinkle, ndi mitundu yosatha ya maluwa a banja la Apocynaceae.
Vincristine ndi alkaloid yachilengedwe ndipo imagwiritsidwa ntchito ngati mankhwala a chemotherapy kuchiza mitundu yosiyanasiyana ya khansa, kuphatikizapo khansa ya m'magazi, lymphoma, ndi zotupa zolimba. Zimagwira ntchito posokoneza kukula kwa maselo a khansa.

Kufotokozera (COA)

Zomwe Zimagwira Ntchito mu Chitchaina Dzina lachingerezi CAS No. Kulemera kwa Maselo Molecular Formula
长春胺 Vincamine 1617-90-9 354.44 Chithunzi cha C21H26N2O3
脱水长春碱 Anhydrovinblastine 38390-45-3 792.96 Chithunzi cha C46H56N4O8
異長春花苷內酰胺 Mankhwala "Strictosamide" 23141-25-5 498.53 Chithunzi cha C26H30N2O8
四氢鸭脚木碱 Tetrahydroalstonine 6474-90-4 352.43 Chithunzi cha C21H24N2O3
酒石酸长春瑞滨 Vinorelbine tartrate 125317-39-7 1079.12 C45H54N4O8.2(C4H6O6);C
长春瑞滨 Vinorelbine 71486-22-1 778.93 Chithunzi cha C45H54N4O8
长春新碱 Vincristine 57-22-7 824.96 Chithunzi cha C46H56N4O10
硫酸长春新碱 Vincristine sulphate 2068-78-2 923.04 Chithunzi cha C46H58N4O14S
硫酸长春质碱 Catharanthini sulfate 70674-90-7 434.51 Chithunzi cha C21H26N2O6S
酒石酸长春质碱 Catharanthine hemitartrate 4168-17-6 486.51 C21H24N2O2.C4H6O6
长春花碱 Vinblastine 865-21-4 810.99 Chithunzi cha C46H58N4O9
长春质碱 Catharanthine 2468-21-5 336.43 Chithunzi cha C21H24N2O2
文朵灵 Vindoline 2182-14-1 456.53 Chithunzi cha C25H32N2O6
硫酸长春碱 Vinblastine sulfate 143-67-9 909.05 Chithunzi cha C46H60N4O13S
β-谷甾醇 β-Sitosterol 83-46-5 414.71 C29H50O
菜油甾醇 Kampesterol 474-62-4 400.68 C28H48O
齐墩果酸 Oleanolic acid 508-02-1 456.7 C30H48O3

 

KUKHALA KWA PRODUCT
Dzina lazogulitsa: Vinca rosea chimodzimodzi
Dzina la Botanic: Catharanthus roseus (L.)
Gawo la chomera Maluwa
Dziko lakochokera: China
KUSANGALALA ZINTHU MFUNDO NJIRA YOYESA
Maonekedwe Ufa wabwino Organoleptic
Mtundu Brown fine powder Zowoneka
Kununkhira & Kukoma Khalidwe Organoleptic
Chizindikiritso Zofanana ndi zitsanzo za RS Zithunzi za HPTLC
Kutulutsa Mlingo 4:1–20:1; Vincristine 98% min
Sieve Analysis 100% mpaka 80 mauna USP39 <786>
Kutaya pakuyanika ≤ 5.0% Eur.Ph.9.0 [2.5.12]
Zonse Ash ≤ 5.0% Eur.Ph.9.0 [2.4.16]
Kutsogolera (Pb) ≤ 3.0 mg/kg Eur.Ph.9.0<2.2.58>ICP-MS
Arsenic (As) ≤ 1.0 mg/kg Eur.Ph.9.0<2.2.58>ICP-MS
Cadmium (Cd) ≤ 1.0 mg/kg Eur.Ph.9.0<2.2.58>ICP-MS
Mercury (Hg) ≤ 0.1 mg/kg -Reg.EC629/2008 Eur.Ph.9.0<2.2.58>ICP-MS
Chitsulo cholemera ≤ 10.0 mg/kg Eur.Ph.9.0<2.4.8>
Zotsalira Zosungunulira Sinthani Eur.ph. 9.0 <5,4> ndi EC European Directive 2009/32 Eur.Ph.9.0<2.4.24>
Zotsalira Zophera tizilombo Conform Regulations(EC) No.396/2005kuphatikiza zowonjezera ndi zosintha zotsatizana

Reg.2008/839/CE

Gasi Chromatography
Aerobic bacteria (TAMC) ≤10000 cfu/g USP39 <61>
Yisiti/Nkhungu (TAMC) ≤1000 cfu/g USP39 <61>
Escherichia coli: Palibe mu 1g USP39 <62>
Salmonella spp: Palibe mu 25 g USP39 <62>
Staphylococcus aureus: Palibe mu 1g
Listeria Monocytogenens Palibe mu 25 g
Aflatoxins B1 ≤ 5 ppb -Reg.EC 1881/2006 USP39 <62>
Aflatoxins ∑ B1, B2, G1, G2 ≤ 10 ppb -Reg.EC 1881/2006 USP39 <62>

Zogulitsa Zamankhwala

Zogulitsa za Vinca Rosea Extract Vincristine zingaphatikizepo:
Kuyera kwambiri:Zogulitsa za Vincristine nthawi zambiri zimakhala zoyera kwambiri ndipo zimatsatira mfundo zokhwima zopangira mankhwala kuti zitsimikizire chiyero ndi kukhazikika kwa mankhwalawa.
Kupezeka kochokera:Vincristine nthawi zambiri amachotsedwa ku chomera cha Catharanthus roseus. Kapangidwe kake kamakhala kosavuta ndipo kumagwirizana ndi kusonkhanitsa ndi kupanga zinthu zamankhwala a botanical.
Kukhazikika kwa Chemical:Monga gulu la alkaloid, vincristine ili ndi kukhazikika kwa mankhwala abwino ndipo ndi yoyenera kupanga mankhwala ndi kusungidwa kwa nthawi yaitali.
Anti-chotupa ntchito:Monga mankhwala odana ndi chotupa, vincristine ali ndi ntchito yolepheretsa kukula ndi kufalikira kwa maselo otupa ndipo ndi oyenera kuchiza khansa zosiyanasiyana.
Chitsimikizo chachipatala:Vincristine yatsimikiziridwa mwachipatala ndipo imagwiritsidwa ntchito kwambiri pazachipatala, ndi chithandizo chodalirika chamankhwala ndi chithandizo chamankhwala.
Makhalidwe a mankhwalawa amawonetsa ubwino, ntchito, ndi kufunika kwachipatala kwa vincristine monga mankhwala ofunika kwambiri odana ndi khansa.

Ubwino Wathanzi

Vinca Rosea Extract Vincristine imadziwika kwambiri chifukwa chamankhwala ake pochiza khansa ndipo sikuti nthawi zambiri imakhudzana ndi thanzi lachindunji pakugwiritsa ntchito ogula. Vincristine, wochokera ku chomera cha Vinca rosea, ndi mankhwala amphamvu a chemotherapy omwe amagwiritsidwa ntchito pochiza mitundu yosiyanasiyana ya khansa, kuphatikizapo khansa ya m'magazi, lymphoma, ndi zotupa zolimba. Zimagwira ntchito posokoneza kukula kwa maselo a khansa.

Ndikofunika kuzindikira kuti Vincristine ndi mankhwala omwe amaperekedwa moyang'aniridwa ndi akatswiri azachipatala, ndipo kugwiritsidwa ntchito kwake kumayenderana ndi zotsatirapo zake komanso kuopsa kwake. Choncho, nthawi zambiri sagulitsidwa kapena kudyedwa chifukwa cha ubwino wake wa thanzi kunja kwa zochitika zachipatala.

Mapulogalamu

Kugwiritsa ntchito mwatsatanetsatane kwa Vinca Rosea Extract Vincristine ndi:
Chithandizo cha Khansa:Vincristine amagwiritsidwa ntchito makamaka pochiza mitundu yosiyanasiyana ya khansa, kuphatikizapo khansa ya m'magazi, lymphoma, ndi zotupa zolimba. Amagwiritsidwa ntchito ngati gawo la chemotherapy regimens kuti alepheretse kukula kwa maselo a khansa.
Kafukufuku wa Zamankhwala:Chotsitsacho chimagwiritsidwa ntchito pofufuza zamankhwala popanga chithandizo chatsopano cha khansa komanso kuphunzira momwe amagwirira ntchito.
Chemistry Yamankhwala:Vincristine amagwira ntchito ngati gawo lamtengo wapatali pazamankhwala amankhwala, zomwe zimathandizira pakupanga mankhwala atsopano komanso othandizira achire.
Biotechnology:Chotsitsacho chikhoza kugwiritsidwa ntchito pazachilengedwe, monga kupanga mankhwala oletsa khansa komanso njira zoperekera mankhwala.
Mayesero Achipatala:Vincristine amatenga nawo mbali m'mayesero azachipatala kuti awone momwe imathandizira pochiza mitundu yosiyanasiyana ya khansa ndikufufuza zomwe zingagwiritsidwe ntchito pazinthu zina zamankhwala.
Kupanga Mankhwala:The Tingafinye ntchito mu chiphunzitso cha mankhwala mankhwala, kuphatikizapo jekeseni njira ndi mitundu ina mlingo wa mankhwala khansa.
Mapulogalamuwa akuwonetsa kugwiritsa ntchito kosiyanasiyana kwa Vinca Rosea Extract Vincristine pochiza khansa, kafukufuku wamankhwala, ndi chitukuko cha mankhwala.

Zomwe Zingatheke

Vincristine ndi mankhwala amphamvu a chemotherapy, ndipo kugwiritsidwa ntchito kwake kumatha kulumikizidwa ndi zotsatirapo zingapo. Zina mwazotsatira za ufa wa Vincristine zingaphatikizepo:
Neurotoxicity:Vincristine imatha kuwononga dongosolo lamanjenje lamkati, zomwe zimayambitsa zizindikiro monga dzanzi, kumva kulasalasa, komanso kufooka m'miyendo.
Zotsatira Zam'mimba:Zotsatira zofala za m'mimba zingaphatikizepo nseru, kusanza, kudzimbidwa, ndi kupweteka kwa m'mimba.
Kuponderezedwa kwa Bone Marrow:Vincristine imatha kupondereza mafupa, zomwe zimapangitsa kuchepa kwa maselo a magazi, zomwe zingayambitse kuchepa kwa magazi, kuwonjezereka kwa matenda, komanso kutulutsa magazi.
Kutaya Tsitsi:Anthu ena amatha kuthothoka tsitsi kapena kuwonda chifukwa cha mankhwala a Vincristine.
Kupweteka kwa Chibwano:Vincristine ikhoza kuyambitsa mtundu wina wa ululu womwe umadziwika kuti "vincristine-induced neuropathy-acute-onset," yomwe imadziwika ndi kupweteka kwa nsagwada ndi zovuta kumeza.
Zina Zomwe Zingachitike:Zotsatira zina zowonjezera zingaphatikizepo kufooka kwa minofu, kusintha kwa kuthamanga kwa magazi, ndi ziwengo.
Ndikofunika kuzindikira kuti mndandanda womwe uli pamwambawu siwokwanira, ndipo akatswiri azachipatala ayenera kuyang'anitsitsa anthu omwe amalandira Vincristine pazochitika zilizonse zomwe zingachitike. Zotsatira zake zenizeni komanso kuuma kwawo kumatha kusiyana ndi munthu. Odwala ayenera kukambirana za zotsatirapo ndi nkhawa zawo ndi wothandizira zaumoyo asanayambe chithandizo cha Vincristine.


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    * Nthawi Yobweretsera: Pafupifupi masiku 3-5 ogwira ntchito mutalipira.
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    * Kulemera Kwambiri: 25kgs / ng'oma, Kulemera Kwambiri: 28kgs / Drum
    Kukula kwa Drum & Volume: ID42cm × H52cm, 0.08 m³/ Drum
    * Kusungirako: Kusungidwa pamalo owuma komanso ozizira, khalani kutali ndi kuwala kwamphamvu ndi kutentha.
    * Shelf Life: Zaka ziwiri zikasungidwa bwino.

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