Vinca Rosea Extract Vincristine
Vinca Rosea Extract Vincristine amatanthauza mankhwala opangidwa ndi Vincristine, omwe amachokera ku chomera cha periwinkle (Vinca rosea), chomwe chimadziwikanso kuti Catharanthus roseus, bright eyes, Cape periwinkle, graveyard plant, Madagascar periwinkle, old maid, pink periwinkle, rose periwinkle, ndi mtundu wa zomera zosatha zomwe zimakhala ndi maluwa m'banja la Apocynaceae.
Vincristine ndi alkaloid yachilengedwe ndipo imagwiritsidwa ntchito ngati mankhwala a chemotherapy pochiza mitundu yosiyanasiyana ya khansa, kuphatikizapo khansa ya m'magazi, khansa ya m'magazi, ndi zotupa zolimba. Imagwira ntchito posokoneza kukula kwa maselo a khansa.
| Zosakaniza Zazikulu Zogwira Ntchito mu Chitchaina | Dzina la Chingerezi | Nambala ya CAS | Kulemera kwa Maselo | Fomula ya Maselo |
| 长春胺 | Vincamine | 1617-90-9 | 354.44 | C21H26N2O3 |
| 脱水长春碱 | Anhydrovinblastine | 38390-45-3 | 792.96 | C46H56N4O8 |
| 異長春花苷內酰胺 | Strictosamide | 23141-25-5 | 498.53 | C26H30N2O8 |
| 四氢鸭脚木碱 | Tetrahydroalstonine | 6474-90-4 | 352.43 | C21H24N2O3 |
| 酒石酸长春瑞滨 | Vinorelbine Tartrate | 125317-39-7 | 1079.12 | C45H54N4O8.2(C4H6O6);C |
| 长春瑞滨 | Vinorelbine | 71486-22-1 | 778.93 | C45H54N4O8 |
| 长春新碱 | Vincristine | 57-22-7 | 824.96 | C46H56N4O10 |
| 硫酸长春新碱 | Vincristine sulfate | 2068-78-2 | 923.04 | C46H58N4O14S |
| 硫酸长春质碱 | Catharanthine Sulfate | 70674-90-7 | 434.51 | C21H26N2O6S |
| 酒石酸长春质碱 | Catharanthine hemitartrate | 4168-17-6 | 486.51 | C21H24N2O2.C4H6O6 |
| 长春花碱 | Vinblastine | 865-21-4 | 810.99 | C46H58N4O9 |
| 长春质碱 | Katharanthine | 2468-21-5 | 336.43 | C21H24N2O2 |
| 文朵灵 | Vindoline | 2182-14-1 | 456.53 | C25H32N2O6 |
| 硫酸长春碱 | Vinblastine Sulfate | 143-67-9 | 909.05 | C46H60N4O13S |
| β-谷甾醇 | β-Sitosterol | 83-46-5 | 414.71 | C29H50O |
| 菜油甾醇 | Campesterol | 474-62-4 | 400.68 | C28H48O |
| 齐墩果酸 | Asidi wa Oleanolic | 508-02-1 | 456.7 | C30H48O3 |
| ZOKHUDZA ZA CHOTENGERA | ||
| Dzina la Chinthu: | Vinca rosea yeniyeni | |
| Dzina la Botanical: | Catharanthus roseus (L.) | |
| Gawo la chomera | Duwa | |
| Dziko lakochokera: | China | |
| ZINTHU ZOSANTHULA | ZOKHUDZA | NJIRA YOYESERA |
| Maonekedwe | Ufa wabwino | Organoleptic |
| Mtundu | Ufa wofiirira wabwino | Zooneka |
| Fungo ndi Kukoma | Khalidwe | Organoleptic |
| Kudziwika | Chofanana ndi chitsanzo cha RS | HPTLC |
| Chiŵerengero Chochotsera | 4:1~20:1; Vincristine 98%min | |
| Kusanthula kwa Sieve | 100% mpaka 80 maukonde | USP39 <786> |
| Kutayika pakuuma | ≤ 5.0% | Euro.Ph.9.0 [2.5.12] |
| Phulusa Lonse | ≤ 5.0% | Euro.Ph.9.0 [2.4.16] |
| Mtsogoleli (Pb) | ≤ 3.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Arsenic (As) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Cadmium (Cd) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Mercury (Hg) | ≤ 0.1 mg/kg -Reg.EC629/2008 | Eur.Ph.9.0<2.2.58>ICP-MS |
| Chitsulo cholemera | ≤ 10.0 mg/kg | Yuro.Ph.9.0<2.4.8> |
| Zotsalira za Zosungunulira | Kutsatira Eur.ph. 9.0 <5,4 > ndi EC European Directive 2009/32 | Yuro.Ph.9.0<2.4.24> |
| Zotsalira za Mankhwala Ophera Tizilombo | Kutsatira Malamulo (EC) Nambala 396/2005 kuphatikiza zowonjezera ndi zosintha zotsatizana Reg.2008/839/CE | Chromatography ya Gasi |
| Mabakiteriya a aerobic (TAMC) | ≤10000 cfu/g | USP39 <61> |
| Yisiti/Zinthu Zopangira (TAMC) | ≤1000 cfu/g | USP39 <61> |
| Escherichia coli: matenda a Escherichia coli: | Palibe mu 1g | USP39 <62> |
| Salmonella spp: | Palibe mu 25g | USP39 <62> |
| Staphylococcus aureus: matenda a bakiteriya | Palibe mu 1g | |
| Listeria Monocytogenens | Palibe mu 25g | |
| Aflatoxin B1 | ≤ 5 ppb -Reg.EC 1881/2006 | USP39 <62> |
| Aflatoxins ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | USP39 <62> |
Zinthu zomwe zili mu Vinca Rosea Extract Vincristine zitha kukhala ndi izi:
Kuyera kwambiri:Zinthu za Vincristine nthawi zambiri zimakhala zoyera kwambiri ndipo zimagwirizana ndi miyezo yokhwima yopangira mankhwala kuti zitsimikizire kuti mankhwalawa ndi oyera komanso okhazikika.
Kutsata komwe kumachokera:Vincristine nthawi zambiri imachokera ku chomera cha Catharanthus roseus. Njira yake yopangira imadziwika bwino ndipo imagwirizana ndi zomwe zasonkhanitsidwa ndi kupangidwa kwa mankhwala a zomera.
Kukhazikika kwa mankhwala:Monga mankhwala a alkaloid, vincristine ili ndi mankhwala okhazikika bwino ndipo ndi yoyenera kupanga mankhwala komanso kusungidwa kwa nthawi yayitali.
Ntchito yolimbana ndi chotupa:Monga mankhwala oletsa chotupa, vincristine ili ndi ntchito yoletsa kukula ndi kufalikira kwa maselo a chotupa ndipo ndi yoyenera kuchiza khansa zosiyanasiyana.
Kutsimikizira zachipatala:Vincristine yatsimikiziridwa ndi madokotala ndipo imagwiritsidwa ntchito kwambiri mu zamankhwala, ndi chithandizo chodalirika cha mankhwala ndi zotsatira zachipatala.
Makhalidwe a mankhwalawa akuwonetsa ubwino, ntchito, ndi kufunika kwa vincristine monga mankhwala ofunikira oletsa khansa.
Vinca Rosea Extract Vincristine imadziwika kwambiri chifukwa cha ntchito zake zamankhwala pochiza khansa ndipo nthawi zambiri sizimagwirizanitsidwa ndi ubwino wa thanzi kwa anthu onse. Vincristine, yochokera ku chomera cha Vinca rosea, ndi mankhwala amphamvu a chemotherapy omwe amagwiritsidwa ntchito pochiza mitundu yosiyanasiyana ya khansa, kuphatikizapo khansa ya m'magazi, khansa ya m'magazi, ndi zotupa zolimba. Imagwira ntchito posokoneza kukula kwa maselo a khansa.
Ndikofunika kudziwa kuti Vincristine ndi mankhwala operekedwa ndi dokotala omwe amaperekedwa moyang'aniridwa ndi akatswiri azaumoyo, ndipo kugwiritsidwa ntchito kwake kumakhudzana ndi zotsatirapo zake komanso zoopsa zake. Chifukwa chake, nthawi zambiri samagulitsidwa kapena kugwiritsidwa ntchito chifukwa cha ubwino wake paumoyo kunja kwa malo azachipatala.
Magwiritsidwe ntchito a Vinca Rosea Extract Vincristine mwatsatanetsatane ndi awa:
Chithandizo cha Khansa:Mankhwala a Vincristine amagwiritsidwa ntchito makamaka pochiza mitundu yosiyanasiyana ya khansa, kuphatikizapo khansa ya m'magazi, khansa ya m'magazi, ndi zotupa zolimba. Amaperekedwa ngati gawo la mankhwala a chemotherapy kuti aletse kukula kwa maselo a khansa.
Kafukufuku wa Mankhwala:Chotsitsachi chimagwiritsidwa ntchito pofufuza zamankhwala popanga mankhwala atsopano a khansa komanso kuphunzira momwe amagwirira ntchito.
Mankhwala a Chemistry:Vincristine ndi mankhwala ofunika kwambiri m'munda wa mankhwala, zomwe zimathandiza pakupanga mankhwala atsopano komanso mankhwala ochiritsira.
Ukadaulo wa Zamoyo:Chotsitsacho chingagwiritsidwe ntchito pa ntchito za biotechnology, monga kupanga mankhwala oletsa khansa ndi njira zoperekera mankhwala.
Mayeso azachipatala:Vincristine imagwira nawo ntchito zoyesa zachipatala kuti ifufuze momwe imagwirira ntchito pochiza mitundu yosiyanasiyana ya khansa komanso kufufuza momwe ingagwiritsidwire ntchito pa matenda ena.
Kupanga Mankhwala:Chotsitsacho chimagwiritsidwa ntchito popanga mankhwala, kuphatikizapo njira zobayira jakisoni ndi mitundu ina ya mlingo wa mankhwala a khansa.
Ntchito izi zikuwonetsa momwe Vinca Rosea Extract Vincristine imagwiritsidwira ntchito pochiza khansa, kafukufuku wa mankhwala, komanso kupanga mankhwala.
Vincristine ndi mankhwala amphamvu a chemotherapy, ndipo kugwiritsidwa ntchito kwake kungagwirizane ndi zotsatirapo zingapo. Zina mwa zotsatirapo zoyipa za ufa wa Vincristine zitha kukhala:
Kuopsa kwa ubongo:Vincristine ikhoza kuwononga dongosolo lamanjenje la m'mphepete mwa thupi, zomwe zimapangitsa kuti pakhale zizindikiro monga dzanzi, kumva kuwawa, komanso kufooka m'miyendo ndi miyendo.
Zotsatira za m'mimba:Zotsatira zoyipa zomwe zimapezeka m'mimba zimatha kuphatikizapo nseru, kusanza, kudzimbidwa, ndi kupweteka m'mimba.
Kuletsa Mafuta a M'mafupa:Vincristine imatha kuletsa mafuta m'mafupa, zomwe zimapangitsa kuti maselo amagazi achepe, zomwe zingayambitse kuchepa kwa magazi m'thupi, kuwonjezeka kwa matenda opatsirana, komanso chizolowezi chotuluka magazi m'thupi.
Kutaya Tsitsi:Anthu ena amatha kutaya tsitsi kapena kuonda chifukwa cha chithandizo cha Vincristine.
Ululu wa Nsagwada:Vincristine ingayambitse mtundu wina wa ululu wotchedwa "vincristine-induced neuropathy-acute-onset," womwe umadziwika ndi kupweteka kwa nsagwada komanso kuvutika kumeza.
Zotsatira Zina Zomwe Zingakhalepo:Zotsatira zina zoyipa zingaphatikizepo kufooka kwa minofu, kusintha kwa kuthamanga kwa magazi, ndi ziwengo.
Ndikofunika kudziwa kuti mndandanda womwe uli pamwambapa suli wokwanira, ndipo akatswiri azaumoyo ayenera kuyang'anira mosamala anthu omwe akumwa Vincristine kuti aone ngati pali zotsatirapo zilizonse zomwe zingachitike. Zotsatirapo zake komanso kuopsa kwake zimatha kusiyana malinga ndi munthu aliyense. Odwala ayenera kukambirana za zotsatirapo zake ndi nkhawa zomwe zingachitike ndi dokotala wawo asanayambe kulandira chithandizo cha Vincristine.
Kulongedza ndi Kutumikira
Kulongedza
* Nthawi Yotumizira: Pafupifupi masiku 3-5 ogwira ntchito mutalipira.
* Phukusi: Mu ng'oma za ulusi ndi matumba awiri apulasitiki mkati.
* Kulemera Konse: 25kgs/ng'oma, Kulemera Konse: 28kgs/ng'oma
* Kukula kwa Ng'oma ndi Kuchuluka: ID42cm × H52cm, 0.08 m³/ Ng'oma
* Kusungira: Kusungidwa pamalo ouma komanso ozizira, sungani kutali ndi kuwala kwamphamvu ndi kutentha.
* Moyo wa Shelufu: Zaka ziwiri zikasungidwa bwino.
Manyamulidwe
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Njira Zolipirira ndi Kutumiza
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Zolemera zosakwana 100kg, masiku 3-5
Utumiki wosavuta kutenga katundu pakhomo ndi khomo
Panyanja
Kupitirira 300kg, Pafupifupi masiku 30
Pakufunika katswiri wopereka chilolezo kuchokera ku doko kupita ku doko
Ndi Ndege
100kg-1000kg, Masiku 5-7
Pakufunika katswiri wopereka chithandizo kuchokera ku eyapoti kupita ku eyapoti
Tsatanetsatane wa Kupanga (Tchati cha Kuyenda)
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3. Kuika maganizo ndi kuyeretsa
4. Kuuma
5. Kukhazikitsa miyezo
6. Kuwongolera Ubwino
7. Kulongedza 8. Kugawa
Chitsimikizo
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