Lycorine hydrochloride
Lycorine hydrochloride ndi yoyera yoyera yochokera ku alkaloid lycorine, yomwe imapezeka muzomera za lycoris Radiata (ndi iye.), Ndipo ali a banja la amaryllinaceae. A Lycorine hydrochloride ali ndi zovuta zamakampani zomwe zingachitike, kuphatikiza anti-chotupa, anti-hcv, anti-hcus, anti-anti-malupe Amasungunuka m'madzi, DMSO, ndi Mowa. Dongosolo lake la mankhwala limadziwika ndi mawonekedwe osokoneza bongo okhala ndi zolaula zowawa ndi magulu angapo ogwira ntchito, kuphatikizapo ma hydroxyl ndi magwiridwe antchito, ndikupereka zochitika zake zachilengedwe.
| Dzina lazogulitsa | Lycorine hydrochloride cas: 2188-68-3 | ||
| Chiyambi cha chomera | Lycoris | ||
| Kusunga | Sungani ndi chidindo firiji kutentha | Lipoti | 2024.08.24 |
| Chinthu | Wofanana | Malipiro |
| Kukhala Uliwala(Hplc) | Lycorine hydrochloride≥98% | 99.7% |
| Kaonekedwe | Ufa woyera | Zogwirizana |
| Kakhalidwe kathupiochelitsa | ||
| Kukula kwa tinthu | Nlt100% 80Mau | Zogwirizana |
| Kutayika pakuyanika | ≤1.0% | 1.8% |
| Cholemera chitsulo | ||
| Zitsulo zonse | ≤10.0ppm | Zogwirizana |
| Tsogoza | ≤2.0PPM | Zogwirizana |
| Mercury | ≤1.0PPM | Zogwirizana |
| Cadmium | ≤0.5ppm | Zogwirizana |
| Tizilombo ta microorganism | ||
| Chiwerengero chonse cha mabakiteriya | ≤1000cfu / g | Zogwirizana |
| Yisiti | ≤100cfu / g | Zogwirizana |
| Escrivehia Coli | Osaphatikizidwa | Osapezeka |
| Nsomba monomolla | Osaphatikizidwa | Osapezeka |
| StaphylococCus | Osaphatikizidwa | Osapezeka |
| Chidule | Wokwanira | |
Mawonekedwe:
(1) Chiyero chachikulu:Zogulitsa zathu zimakonzedwa mosamala kuti zitsimikizire kuti kuchuluka kwa chiyero chachikulu, chomwe ndichofunikira kwambiri pakugwira kwake ndi chitetezo chake pamapulogalamu osiyanasiyana.
(2) Katundu wa Anticancer:Ikuwonetsa zotsatira za khansa zosiyanasiyana za khansa, mu vivo ndi ku Vivo ndi ku Vivo, kudzera mu vivoge, kuyika apoptissis, ndikuletsa angiogenesis.
(3) Zochita zingapo:Lycorine hydrochloride amakhulupirira kuti amalumikizana ndi zingwe zingapo zazosamwa, zomwe zimapereka mawonekedwe owoneka bwino molingana ndi maselo a khansa.
(4) zoopsa zochepa:Imawonetsa zoopsa pang'ono maselo wamba, zomwe ndizofunikira pakugwiritsa ntchito ngati othandizira.
(5) Mbiri ya pharmacokinetic:Zogulitsa zakhala zikuphunziridwa chifukwa cha pharmacokinetics yake, akuwonetsa mayamwidwe mwachangu komanso kuchotsedwa kwambiri kuchokera ku plasma, zomwe ndizofunikira pakukonzekera ndi kakonzedwe kake.
(6) Zotsatira zoyipa:Lycorine hydrochloride yawonetsa zotsatira zolimbikitsidwa mukamagwiritsidwa ntchito limodzi ndi mankhwala ena, omwe amatha kukhala opindulitsa pakuthana ndi kugwiritsa ntchito mankhwala osokoneza bongo ndikusintha zotsatira zake.
(7) Kufufuza:Chogulitsacho chimathandizidwa ndi kafukufuku wamkulu, kupereka maziko olimba kuti agwiritsidwe ntchito pa chitukuko cha mankhwala komanso kugwiritsa ntchito mankhwala azachipatala.
(8) Chitsimikizo Chachikulu:Njira zolimbitsa thupi zolimbitsa thupi zili m'malo onse opanga kuti muwonetsetse kusintha komanso kudalirika kwa malonda.
(9) Ntchito Zosiyanasiyana:Zoyenera kugwiritsa ntchito pofufuza ndi chitukuko cha ntchito mankhwala opangira mankhwala, kuphatikizapo kupezeka kwa mankhwala osokoneza bongo komanso chitukuko cha khansa.
(10) kutsatira:Kupanga kutsatira mapulogalamu a GPM kuti mutsimikizire kuti chitetezo chambiri ndichabwino.
(1) Makampani ogulitsa mankhwala:Lycorine hydrochloride imagwiritsidwa ntchito popanga mankhwala antiviral ndi anticancer mankhwala.
(2) Mafakitale a Biotechnology:Zimagwiritsidwa ntchito pofufuza ndi chitukuko cha othandizira atsopano achire ndi mapangidwe osokoneza bongo.
(3) Zachilengedwe Zogulitsa:Lycorine hydrochloride amaphunziridwa chifukwa cha phindu lake lathanzi ndi mankhwala.
(4) Makampani amakampani:Itha kugwiritsidwa ntchito ngati gawo lapakati pa kapangidwe kazinthu zina.
(5) Makampani olimaLycorine hydrochloride yafufuzidwa kuti ithe ngati mankhwala ophera tizilombo ndi chowonjezera chomera.
Njira yodulira ya Lycorine hydrochloride nthawi zambiri imaphatikizapo njira zotsatirazi zowonetsetsa kuti zosungunulira ndi kukonza bwino kwambiri:
.Sankhani Aaryllidaceae zomera zomera, monga mababu a Amaryllis, ndikusamba, owuma ndikuwaphwanya kuti awonetsetse kuti ziweto zaiwisi ndikuyika maziko a m'zipepala.
(2)Wophatikiza enzyme zodzikongoletsera:Gwiritsani ntchito michere yovuta (monga pectinase ndi pectinase) kuti musangalatse zida zosweka kuti muwongolere makhoma a cell ndikusinthasintha.
(3)Drite hydrochloric acid zoyambirira:Sakanizani zida zokongoletsedwa ndi kuchepetsa hydrochloric acid yankho la kutulutsa Lycorine. Kugwiritsa ntchito ma hydrochloric acid kumathandizira kuwonjezera kusungunuka kwa Lycorine, potero kumawonjezera mphamvu yothandiza.
(4)Akupanga -Kugwiritsa ntchito ukadaulo wa akupanga - kumathandizira kusunthika kwa Lycorine mu zosungunulira ndikusintha mphamvu bwino komanso chiyero.
(5)Chloroform powonjezera:Chotsani chimachitika ndi ma soric ordoform monga chloroform, ndipo atcorine amasamutsidwa kuchokera gawo lalikulu kupita ku malo osungira chandamale.
(6)Kuchira:Pambuyo pochotsa njirayi, zosungunulira zimachira kudzera mu Earporation kapena distillation kuti muchepetse kugwiritsa ntchito zosungunulira ndikusintha zachuma.
(7)Kuyeretsa ndi Kuyanika:Kudzera mu chiyeretso choyenera komanso kuyanika masitepe, lycorine hydrochloride ufa wapezeka.
Pazinthu zonse zowonjezera, zomwe zimawongolera kusankha, zomwe zimapatulidwa (monga pH yamtengo wapatali, kutentha, ndi nthawi), ndipo zoyeretsa zotsatizana ndi kukonza chiyero. Kugwiritsa ntchito zida zamakono komanso zida zoyeretsa, monga njira zopangira ma promatography komanso ma chplc.
Kusungidwa: Khalani pamalo ozizira, owuma, komanso oyera, kuteteza ku chinyezi komanso kuwala.
Phukusi la Bisi: 25kg / Drum.
Nthawi Yotsogola: Patatha masiku 7 mutayitanitsa.
Moyo wa alumali: zaka 2.
Dzukani: Zida zamakono zitha kupezekanso.
Lankhula
Pansi pa 100kg, 3-5days
Khomo lolowera chitseko chosavuta kunyamula katundu
Mwa nyanja
Onjezerani300kg, pafupifupi masiku 30
Port to Port Services Claker Claker yofunika
Ndi mpweya
100kg-1000kg, 5-7days
Airport kupita ku Airport Service Service Claker Claker yofunika
Bioway Organic yatenga USDA ndi EU Organic, Brc, ISO, Halal, kosher, ndi Halamar.
Aycorine ndi Alkloid mwachilengedwe omwe amatha kupezeka muzomera zingapo, makamaka mkati mwa banja la amaryllinaceae. Nazi zomera zina zomwe zimadziwika kuti zili ndi lycorine:
Lycoris Radiata.
Leucojum astAnt(Chilimwe chipale chofewa), chimadziwikanso kuti kuli lycorine.
Ungernia seewertowiiChomera china kuchokera ku banja la Amaryllidaceae lomwe lanenedwa kuti lili ndi Lycorne.
Hippeastrum hybrid (kakombo wa Isitala)Ndipo mbewu zina zokhudzana ndi Amaryllidaceae ndizodziwika bwino za Lycorine.
Zomera izi zimagawidwa kwambiri m'malo otentha komanso otentha padziko lonse lapansi ndipo ali ndi mbiri yayitali yogwiritsa ntchito mankhwala achikhalidwe. Kukhalapo kwa Lycorine muzomera izi kwakhala nkhani yofufuzira chifukwa cha zomwe zakhalapo ma pharmacolol, kuphatikizapo zovuta zake monga zikuwonetsedwa mu maphunziro osiyanasiyana.
Lycorine ndi alkaloid yachilengedwe yokhala ndi mitundu yosiyanasiyana ya mankhwala, kuphatikizapo ntchito yake yogwiritsa ntchito khansa. Pomwe ikuwonetsa zabwino zopindulitsa pamaphunziro osiyanasiyana, pali zovuta zina zomwe zimachitika ndi zomwe zimakhudzana ndi zomwe amagwiritsa ntchito:
Kuopsa kochepa: Lycorine ndi mchere wake wa hydrochloride amawonetsa zoopsa zotsika, zomwe zimadziwika bwino pakugwiritsa ntchito mankhwala. Zawonetsedwa kukhala ndi zovuta zochepa pa maselo a anthu wamba komanso mbewa zathanzi, ndikuwonetsa kusankhidwa kwina kwa maselo a khansa pa minofu yabwinobwino.
Zotsatira za Emetic Emet: Kusanza kwa mseru ndi kusanza kwawonedwa kotsatira subleine kapena jakisoni wa Lycorine hydrochloride, nthawi zambiri amakhala ndi ndalama zosakwana 2,5.
Palibe mgwirizano wopanda kanthu: Kafukufuku wasonyeza kuti Mlingo wa Sycorine sukukhudza mgwirizano wamagalimoto mu mbewa, zomwe zikuwonetsa kuti sizimapangitsa kuti pakhale mphamvu yamagalimoto.
Kukhudzira ntchito kwa indomotor: Pa mlingo wa 30 mg / kg, lycorine adawonedwa kuti asungunuke oyendetsa ndege mu mbewa, monga zimasonyezera ndi kuchepa kwa machitidwe ndi kuwonjezeretsa kosasinthika.
Khalidwe Lalikulu komanso Kukhala bwino: Mlingo wa 10 mg / kg wa lycorine sunasokoneze magwiridwe antchito komanso kutsimikizira kuti izi zitha kukhala mlingo wolakwika wamtsogolo.
Palibe zovuta zazikulu pamlingo wolemera thupi kapena thanzi: makonzedwe a lycorine ndi lycorine hydrochloride sizinapangitse mavuto azaumoyo pazinthu zotupa.
Ndikofunika kudziwa kuti ngakhale lycorine wawonetsa kuthekera kovuta, kuyesedwa kwa nthawi yayitali kukuchepa. Kafukufuku wina amafunika kumvetsetsa bwino mbiri yake yachitetezo, makamaka kuti mugwiritse ntchito kwa nthawi yayitali komanso zosintha zamankhwala. Zotsatira zoyipa ndi chitetezo cha Lycorine zimatha kukhala zosiyanasiyana kutengera kuchuluka kwa mlingo, njira yoyendetsera, ndi kuledzera kwa munthu. Nthawi zonse werengani ndi akatswiri azaumoyo musanaganize zowonjezera zilizonse kapena chithandizo chanu.
