Corydalis Extract Tetrahydropalmatine (dl-THP)
Tetrahydropalmatine (THP), yomwe imadziwikanso kuti dl-THP, Corydalin hydrochloride, kapena Corydalin Tube Extract, ndi gulu lomwe limatchedwa isoquinoline alkaloid. Amachokera ku tuber ya zitsamba zaku China Corydalis yanhusuo. THP ndi chinthu chakristalo chopanda mtundu kapena chotumbululuka chokhala ndi kukoma kowawa pang'ono komanso kusungunuka kwa 147-149 ° C. Sipasungunuke m'madzi koma amasungunuka kwambiri mu ether, chloroform, ndi ethanol. Mchere wake wa hydrochloride ndi sulphate umasungunuka m'madzi.
THP yaphunziridwa pazotsatira zosiyanasiyana zamankhwala, kuphatikiza ma analgesic, anesthetic, neuroprotective, antiplatelet aggregation, antiulcer, antitumor, and anti-addiction properties. Zimakhulupirira kuti zimakhala ndi zotsatira zake zochepetsera ululu mwa kusintha zochitika zapakati pa dopamine receptor ndipo zawonetsa kuthekera koteteza ma neurons ku kuvulala kwa ischemic. Kuonjezera apo, THP yawonetsa zotsatira za antiplatelet aggregation ndipo yafufuzidwa chifukwa cha kuthekera kwake pochiza zilonda, kulepheretsa kukula kwa maselo a chotupa, ndi kuthandizira kusokoneza bongo.
Ponseponse, Tetrahydropalmatine (dl-THP) ndi gulu lomwe lili ndi mitundu yosiyanasiyana yamankhwala ndipo lakhala likufufuzidwa mozama pazamankhwala omwe angakhale nawo. Kuti mudziwe zambiri funsanigrace@biowaycn.com.
Nawa zinthu zopangidwa ndi Tetrahydropalmatine (THP) komanso mapindu awo azaumoyo:
1. Mankhwala Ochepetsa ululu:THP imawonetsa zotsatira za analgesic posintha zochitika zapakati pa dopamine receptor, kupereka mpumulo wopweteka popanda kuthekera kwakukulu kosokoneza bongo.
2. Zotsatira za Neuroprotective:THP yawonetsa kuthekera koteteza ma neurons ku kuvulala kwa ischemic, kuchepetsa neuronal apoptosis, ndikuchepetsa kuchuluka kwa glutamate muubongo, zomwe zingapangitse kuti ma neuroprotective katundu wake.
3. Antiplatelet Aggregation:THP yapezeka kuti imaletsa kuphatikizika kwa mapulateleti, zomwe zitha kuchepetsa chiopsezo chopanga magazi kuundana komanso zochitika zokhudzana ndi mtima.
4. Chithandizo cha Umoyo Wam'mimba:THP yawonetsa zotsutsana ndi zilonda zam'mimba ndipo imatha kuthandizira kuchepetsa katulutsidwe ka asidi m'mimba, kupereka mpumulo ku zilonda zam'mimba ndi zina zofananira.
5. Zomwe Zingachitike Zotsutsana ndi Zotupa:THP yawonetsa zotsatira za cytotoxic pama cell chotupa, zomwe zikuwonetsa gawo lomwe lingathe kuletsa kukula kwa chotupa.
6. Anti-Addiction Properties:THP yaphunziridwa chifukwa cha kuthekera kwake kuchepetsa zizindikiro zosiya zomwe zimagwirizanitsidwa ndi opioid ndi chizolowezi cholimbikitsa, kupereka lonjezo lachirengedwe choledzeretsa komanso kupewa kuyambiranso.
Izi zikuwonetsa mapindu osiyanasiyana azaumoyo komanso njira zochizira za Tetrahydropalmatine (THP).
Tetrahydropydalin (dl-THP) ndi ya alkaloids ya isoquinoline ndipo ndi alkaloid, makamaka mumtundu wa Corydalis lucidum (Yan Hu Suo), komanso zomera zina monga Stephania rotunda. Zomera izi zimagwiritsidwa ntchito pachikhalidwe chamankhwala achi China.Corydalis ndi chomera chosatha cha herbaceous, 10 mpaka 20 cm wamtali, chokhala ndi ma tubers ozungulira. Miyendo yake yomwe ili pamwamba pake ndi yaifupi komanso yowonda, yokhala ndi sikelo pamwamba pa maziko. Masamba oyambira ndi masamba a cauline amafanana mawonekedwe, okhala ndi mapesi; masamba a cauline ndi osinthika, okhala ndi masamba awiri ndi atatu. Tsamba lachiwiri nthawi zambiri limagawanika mosakwanira ndipo limapindika mozama. Masamba ang'onoang'ono amakhala oblong, oval, kapena oval. Mzere, pafupifupi 2 cm wamtali, wokhala ndi nsonga yakuthwa kapena yakuthwa komanso m'mphepete mwaukhondo. Ma inflorescence ake ndi owoneka ngati raceme, okhala ndi masamba omaliza kapena otsutsana; masambawo ali ndi mawonekedwe a lanceolate; maluwawo ndi ofiira-wofiirira ndipo amakula mopingasa pa tinthu tating'onoting'ono tating'ono, tomwe timatalika pafupifupi 6 mm; kalulu amagwa msanga; ma petals ndi 4 ndipo akunja ndi 2 Magawo ndi okulirapo pang'ono, okhala ndi m'mphepete mwa pinki ndi pakati pa bluish-purple. Pali gawo limodzi lapamwamba, ndipo mchirawo umafikira kumtunda wautali. Kutalika kwa spur kumatenga pafupifupi theka la utali wonse. Magawo awiri amkati ndi ocheperapo kuposa magawo awiri akunja. Mapeto apamwamba ndi bluish-wofiirira ndipo amachiritsidwa, ndipo gawo lapansi ndi pinki; Ma stameni ndi 6, ndipo ulusiwo umalumikizidwa kukhala mitolo iwiri, iliyonse ili ndi 3 anther; ovary ndi lathyathyathya-cylindrical, kalembedwe ndi lalifupi ndi woonda, ndipo manyazi ndi 2, ngati gulugufe wamng'ono. Chipatso chake ndi kapisozi. Corydalis amapangidwa makamaka m'mapiri kapena madambo. Madera omwe amapanga kwambiri akuphatikiza Zhejiang, Hebei, Shandong, Jiangsu, ndi malo ena.
| Kusanthula | Kufotokozera |
| Kuyesa | Tetrahydropalmatine ≥98% |
| Maonekedwe | Ufa wachikasu wopepuka mpaka Ufa woyera |
| Phulusa | ≤0.5% |
| Chinyezi | ≤5.0% |
| Mankhwala ophera tizilombo | Zoipa |
| Zitsulo zolemera | ≤10ppm |
| Pb | ≤2.0ppm |
| As | ≤2.0ppm |
| Kununkhira | Khalidwe |
| Tinthu kukula | 100% mpaka 80 mauna |
| Microbiological: | |
| Chiwerengero cha mabakiteriya | ≤1000cfu/g |
| Bowa | ≤100cfu/g |
| Salmgosella | Zoipa |
| Coli | Zoipa |
Nawa mafakitale ogwiritsira ntchito mankhwala a Tetrahydropalmatine (THP):
1. Zamankhwala:THP imagwiritsidwa ntchito m'makampani opanga mankhwala popanga mankhwala oletsa kupweteka komanso mankhwala oteteza ubongo.
2. Nutraceuticals:THP imagwiritsidwa ntchito m'makampani opanga zakudya popanga zopatsa mphamvu zolimbana ndi ululu komanso chithandizo chamankhwala am'mimba.
3. Biotechnology:THP imapeza ntchito mu biotechnology pofufuza zamankhwala a antiplatelet ndi othandizira omwe angakhalepo a khansa.
4. Zaumoyo:THP imaphatikizidwa muzinthu zachipatala pofuna kuthana ndi kuledzera ndi zizindikiro zosiya zomwe zimagwirizanitsidwa ndi opioid ndi kugwiritsa ntchito stimulant.
5. Zodzoladzola:THP imafufuzidwa mu cosmeceuticals kuti ikhale ndi thanzi la khungu komanso anti-inflammatory application.
Mafakitalewa akuwonetsa kugwiritsa ntchito kosiyanasiyana kwa Tetrahydropalmatine (THP) pakukula kwazinthu zosiyanasiyana komanso kafukufuku.
Zogulitsa zathu zimapangidwa pogwiritsa ntchito njira zowongolera bwino komanso zimatsata miyezo yapamwamba yopangira. Timayika patsogolo chitetezo ndi mtundu wazinthu zathu, kuwonetsetsa kuti zikukwaniritsa zofunikira zamalamulo ndi ziphaso zamakampani. Kudzipereka kumeneku ku khalidwe kumafuna kukhazikitsa chidaliro ndi chidaliro pa kudalirika kwa mankhwala athu. Kapangidwe kake kamakhala motere:
Posungira:Sungani pamalo ozizira, owuma, ndi aukhondo, Tetezani ku chinyezi ndi kuwala kolunjika.
Phukusi Lochuluka:20~25kg / ng'oma.
Nthawi yotsogolera:Masiku 7 mutayitanitsa.
Shelf Life:zaka 2.
Ndemanga:Zosintha mwamakonda zitha kukwaniritsidwa.
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