Kashiamu Yoyera ya Methyltetrahydrofolate (5MTHF-Ca)
Pure Methyltetrahydrofolate Calcium (5-MTHF-Ca) ndi mtundu wa folate womwe uli ndi bioavailable kwambiri ndipo ungagwiritsidwe ntchito mosavuta ndi thupi.Ndi mchere wa calcium wa methyltetrahydrofolate, womwe ndi mawonekedwe a folate m'thupi.Folate ndi vitamini B wofunikira womwe umagwira ntchito yofunika kwambiri pama cell osiyanasiyana, kuphatikiza kaphatikizidwe ka DNA, kupanga maselo ofiira amagazi, komanso magwiridwe antchito amanjenje.
MTHF-Ca nthawi zambiri imagwiritsidwa ntchito ngati chowonjezera chazakudya kuthandizira milingo ya folate mwa anthu omwe amavutika kuti azitha kuyamwa kapena kuyamwa mawonekedwe a folic acid omwe amapezeka muzakudya zolimba ndi zowonjezera.Ndiwothandiza makamaka kwa anthu omwe ali ndi mitundu ina ya ma genetic omwe angasokoneze folate metabolism.
Kuonjezera ndi MTHF-Ca kungathandize kuthandizira thanzi labwino ndi thanzi, makamaka m'madera monga thanzi la mtima, chitukuko cha neural chubu pa nthawi ya mimba, chidziwitso, ndi kuwongolera maganizo.Ndikofunikira kudziwa kuti MTHF-Ca iyenera kugwiritsidwa ntchito motsogozedwa ndi akatswiri azachipatala, makamaka kwa anthu omwe ali ndi matenda enaake kapena omwe amamwa mankhwala enaake.
| Dzina la malonda: | L-5-Methyltetrahydrofolate calcium |
| Mawu ofanana ndi mawu: | 6S-5-Methyltetrahydrofolate calcium;Kashiamu L-5-Methyltetrahydrofolate;Levomefolate calcium |
| Molecular formula: | C20H23CaN7O6 |
| Kulemera kwa Molecular: | 497.52 |
| Nambala ya CAS: | 151533-22-1 |
| Zamkatimu: | ≥ 95.00% ndi HPLC |
| Maonekedwe: | Ufa wakristalo woyera mpaka wopepuka |
| Dziko lakochokera: | China |
| Phukusi: | 20kg / ng'oma |
| Alumali moyo: | Miyezi 24 |
| Posungira: | Sungani pamalo ozizira ndi owuma. |
| Zinthu | Zofotokozera | Zotsatira |
| Maonekedwe | ufa woyera kapena wopanda-woyera | Tsimikizani |
| Chizindikiritso | Zabwino | Tsimikizani |
| Kashiamu | 7.0% -8.5% | 8.4% |
| D-5-methylfolate | ≤1.0 | Sizinazindikirike |
| Zotsalira pakuyatsa | ≤0.5% | 0.01% |
| Madzi | ≤17.0% | 13.5% |
| Kuyesa (HPLC) | 95.0% -102.0% | 99.5% |
| Phulusa | ≤0.1% | 0.05% |
| Chitsulo Cholemera | ≤20 ppm | Tsimikizani |
| Total Plate Count | ≤1000cfu/g | Woyenerera |
| Yeast & Mold | ≤100cfu/g | Woyenerera |
| E.coil | Zoipa | Zoipa |
| Salmonella | Zoipa | Zoipa |
Kupezeka kwakukulu kwa bioavailability:MTHF-Ca ndi folate yopezeka kwambiri, kutanthauza kuti imatha kuyamwa mosavuta ndikugwiritsidwa ntchito ndi thupi.Izi ndizofunikira chifukwa anthu ena amatha kukhala ndi vuto losintha kupanga folic acid kukhala mawonekedwe ake.
Folate yogwira ntchito:MTHF-Ca ndi mawonekedwe a folate, omwe amadziwika kuti methyltetrahydrofolate.Fomu iyi imagwiritsidwa ntchito mosavuta ndi thupi ndipo sichifuna njira zina zosinthira.
Calcium Salt:MTHF-Ca ndi mchere wa calcium, womwe umatanthauza kuti umamangidwa ku calcium.Izi zimapereka phindu lowonjezera la calcium supplementation pamodzi ndi chithandizo cha folate.Calcium ndiyofunikira pa thanzi la mafupa, kugwira ntchito kwa minofu, kufalitsa minyewa, ndi ntchito zina zathupi.
Ndioyenera kwa anthu omwe ali ndi mitundu yosiyanasiyana ya majini:MTHF-Ca ndiyothandiza makamaka kwa anthu omwe ali ndi mitundu ina ya majini yomwe ingasokoneze kagayidwe kachakudya.Kusiyanasiyana kwa majini kumeneku kumatha kukhudza kuthekera kwa thupi kutembenuza folic acid kukhala mawonekedwe ake, kupanga zowonjezera ndi folate yogwira kufunikira.
Imathandizira mbali zosiyanasiyana za thanzi:MTHF-Ca supplementation imatha kuthandizira thanzi labwino komanso thanzi.Ndizopindulitsa makamaka pa thanzi la mtima, chitukuko cha neural chubu pa nthawi ya mimba, kugwira ntchito kwachidziwitso, ndi kuwongolera maganizo.
Pure Methyltetrahydrofolate Calcium (MTHF-Ca) imapereka maubwino angapo azaumoyo:
Thandizo la Folate metabolism:MTHF-Ca ndi folate yopezeka kwambiri komanso yogwira ntchito.Imathandiza kuthandizira kagayidwe kachakudya m'thupi, komwe ndi kofunikira pakuphatikizika kwa DNA, kupanga maselo ofiira amagazi, komanso magwiridwe antchito onse a cell.
Moyo wathanzi:Miyezo yokwanira ya folate ndiyofunikira paumoyo wamtima wamtima.MTHF-Ca supplementation ingathandize kuchepetsa milingo ya homocysteine, amino acid yomwe, ikakwera, imalumikizidwa ndi chiopsezo chowonjezeka cha matenda amtima.
Chithandizo cha mimba:MTHF-Ca ndiyofunikira panthawi yomwe ali ndi pakati, chifukwa imathandizira kupewa kuwonongeka kwa neural chubu pakukula kwa fetus.Ndibwino kuti amayi a msinkhu wobereka awonetsetse kuti ali ndi folate yokwanira, makamaka kumayambiriro kwa mimba.
Kuwongolera maganizo:Folate imagwira ntchito yofunika kwambiri pakupanga ma neurotransmitter.Miyezo yokwanira ya folate imathandizira kupanga serotonin, dopamine, ndi norepinephrine, zomwe ndizofunikira pakuwongolera malingaliro.MTHF-Ca supplementation ikhoza kukhala yopindulitsa kwa anthu omwe ali ndi vuto lamalingaliro, monga kupsinjika maganizo.
Ntchito yozindikira:Folate ndiyofunikira pakugwira ntchito kwachidziwitso komanso thanzi laubongo.MTHF-Ca supplementation imatha kuthandizira kukumbukira, kukhazikika, komanso kuzindikira kwathunthu, makamaka kwa okalamba.
Thandizo lazakudya:MTHF-Ca supplementation ikhoza kukhala yopindulitsa kwa anthu omwe ali ndi kusiyana kwa majini komwe kumakhudza folate metabolism.Anthuwa amatha kukhala ndi vuto losintha kupanga folic acid kukhala mawonekedwe ake.MTHF-Ca imapereka mawonekedwe amtundu wa folate mwachindunji, kudutsa zovuta zilizonse zotembenuka.
Nutraceuticals ndi zakudya zowonjezera:MTHF-Ca imagwiritsidwa ntchito nthawi zambiri ngati chinthu chofunikira pazakudya zopatsa thanzi komanso zopatsa thanzi.Imapereka mtundu wopezeka kwambiri wa folate, wopereka maubwino ambiri azaumoyo, monga tanena kale.
Kulimbitsa chakudya ndi zakumwa:MTHF-Ca imatha kuphatikizidwa muzakudya ndi zakumwa kuti muwalimbikitse ndi folate.Izi ndizofunikira kwambiri pazogulitsa zomwe zimathandizira anthu omwe ali ndi vuto la folate kapena kuchuluka kwa zosowa zam'mimba, monga amayi apakati kapena anthu omwe ali ndi thanzi.
Mapangidwe a mankhwala:MTHF-Ca itha kugwiritsidwa ntchito popanga mankhwala ngati chophatikizira.Itha kugwiritsidwa ntchito pamankhwala omwe amayang'ana zinthu zina zokhudzana ndi kuperewera kwa folate kapena kusokonekera kwa kagayidwe kachakudya, monga kuchepa kwa magazi m'thupi kapena matenda ena amtundu.
Zodzisamalira ndi zodzoladzola:MTHF-Ca nthawi zina imaphatikizidwa muzinthu zodzisamalira komanso zodzoladzola chifukwa cha phindu lomwe lingakhalepo pakhungu.Folate imalowa m'maselo osiyanasiyana a khungu ndipo imatha kuthandizira thanzi lake lonse komanso mawonekedwe ake.
Zakudya za ziweto:MTHF-Ca imathanso kuphatikizidwa muzakudya za ziweto kuti iwonjezere nyama ndi folate.Izi ndizofunikira makamaka kwa mafakitale a ziweto ndi nkhuku, kumene kuonetsetsa kuti zakudya zoyenera kuti zikule bwino ndi thanzi ndizofunikira.
Magawo ogwiritsira ntchitowa akuwunikira kusinthasintha kwa MTHF-Ca komanso kugwiritsidwa ntchito kwake m'mafakitale osiyanasiyana kuthana ndi nkhawa zokhudzana ndi thanzi komanso zosowa zazakudya.Komabe, ndikofunikira kutsatira malangizo oyenera a mlingo ndikukambirana ndi akatswiri mukaphatikiza MTHF-Ca muzopanga zilizonse.
Kupeza zinthu zopangira:Njirayi imayamba ndi kupeza zida zapamwamba kwambiri.Zida zofunika kwambiri popanga MTHF-Ca ndi folic acid ndi mchere wa calcium.
Kutembenuka kwa folic acid kukhala 5,10-Methylenetetrahydrofolate (5,10-MTHF):Folic acid imasinthidwa kukhala 5,10-MTHF kudzera munjira yochepetsera.Izi nthawi zambiri zimaphatikizapo kugwiritsa ntchito zochepetsera monga sodium borohydride kapena zothandizira zina zoyenera.
Kusintha kwa 5,10-MTHF kukhala MTHF-Ca:5,10-MTHF imakhudzidwanso ndi mchere wa calcium woyenera, monga calcium hydroxide kapena calcium carbonate, kupanga Methyltetrahydrofolate Calcium (MTHF-Ca).Izi zimaphatikizapo kusakaniza ma reactants ndikuwalola kuti azichita zinthu molamulidwa, kuphatikiza kutentha, pH, ndi nthawi yochitira.
Kuyeretsa ndi kusefa:Pambuyo pazimenezi, yankho la MTHF-Ca limayang'ana njira zoyeretsera monga kusefera, centrifugation, kapena njira zina zolekanitsa kuti zichotse zonyansa ndi zinthu zomwe zikadakhalapo panthawiyi.
Kuyanika ndi kulimbitsa:Yankho loyeretsedwa la MTHF-Ca limakonzedwanso kuti lichotse chinyezi chochulukirapo ndikulimbitsa chomaliza.Izi zitha kuchitika pogwiritsa ntchito njira monga kupukuta kapena kuumitsa kuzizira, kutengera mtundu womwe mukufuna.
Kuwongolera ndi kuyesa kwabwino:Chogulitsa chomaliza cha MTHF-Ca chimayang'aniridwa ndi njira zowongolera kuti zitsimikizire kuyera, kukhazikika, komanso kutsatira miyezo yapamwamba.Izi zingaphatikizepo kuyesa zonyansa, potency, ndi zina zofunika.
Kupaka ndi kusunga:MTHF-Ca imayikidwa m'mitsuko yoyenera, kuwonetsetsa kuti zolemba ndi zosungirako ziyenera kukhala zokhazikika komanso zokhazikika.Nthawi zambiri amasungidwa pamalo ouma, ozizira kutali ndi dzuwa.
Kusungirako: Sungani pamalo ozizira, owuma, ndi aukhondo, Tetezani ku chinyezi ndi kuwala kwachindunji.
Phukusi lalikulu: 25kg / ng'oma.
Nthawi Yotsogolera: Masiku 7 mutayitanitsa.
Alumali Moyo: 2 years.
Zindikirani: Zosintha mwamakonda zitha kukwaniritsidwa.
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Kashiamu Yoyera ya Methyltetrahydrofolate (5-MTHF-Ca)imatsimikiziridwa ndi satifiketi ya ISO, satifiketi ya HALAL, ndi satifiketi ya KOSHER.
Kusiyana pakati pa m'badwo wachinayi wa folic acid (5-MTHF) ndi chikhalidwe cha folic acid chagona mu kapangidwe kake ka mankhwala ndi bioavailability m'thupi.
Kapangidwe ka Chemical:Traditional folic acid ndi mtundu wa folate wopangidwa womwe umayenera kusinthidwa kangapo m'thupi usanagwiritsidwe ntchito.Kumbali inayi, folic acid ya m'badwo wachinayi, yomwe imadziwikanso kuti 5-MTHF kapena Methyltetrahydrofolate, ndiyomwe imagwira ntchito, yopezeka ndi bioavailable ya folate yomwe safuna kutembenuka.
Bioavailability:Traditional folic acid iyenera kusinthidwa kukhala mawonekedwe ake, 5-MTHF, kudzera muzochita za enzymatic m'thupi.Kutembenuka kumeneku kumasiyana pakati pa anthu ndipo kungakhudzidwe ndi kusiyana kwa majini kapena zinthu zina.Mosiyana ndi izi, 5-MTHF ili kale mu mawonekedwe ake, ndikupangitsa kuti ipezeke mosavuta kuti itengeke ndikugwiritsa ntchito ma cellular.
Kuyamwa ndi kugwiritsa ntchito:Mayamwidwe a folic acid achikhalidwe amapezeka m'matumbo ang'onoang'ono, pomwe amafunika kusinthidwa kukhala mawonekedwe okhazikika ndi enzyme dihydrofolate reductase (DHFR).Komabe, kutembenuka kumeneku sikothandiza kwambiri kwa anthu ena, zomwe zimapangitsa kuti bioavailability ikhale yochepa.5-MTHF, pokhala mawonekedwe ogwira ntchito, imatengedwa mosavuta ndikugwiritsidwa ntchito ndi thupi, kudutsa njira yotembenuka.Izi zimapangitsa kukhala mawonekedwe okondedwa kwa anthu omwe ali ndi kusiyana kwa majini kapena mikhalidwe yomwe imakhudza kagayidwe kachakudya ka folate.
Kulimbitsa thupi kwa anthu ena:Chifukwa cha kusiyana kwa mayamwidwe ndi kagwiritsidwe ntchito, 5-MTHF imadziwika kuti ndi yoyenera kwa anthu omwe ali ndi mitundu ina ya majini, monga kusintha kwa jini ya MTHFR, yomwe ingasokoneze kutembenuka kwa folic acid kukhala mawonekedwe ake.Kwa anthuwa, kugwiritsa ntchito 5-MTHF mwachindunji kumatha kuwonetsetsa kuti ma folate ali oyenera m'thupi ndikuthandizira ntchito zosiyanasiyana zachilengedwe.
Zowonjezera:Traditional folic acid imapezeka muzowonjezera, zakudya zolimbitsa thupi, ndi zakudya zokonzedwa, chifukwa zimakhala zokhazikika komanso zotsika mtengo kupanga.Komabe, pakukula kupezeka kwa zowonjezera za 5-MTHF zomwe zimapereka mawonekedwe okhazikika mwachindunji, zomwe zitha kukhala zopindulitsa kwa anthu omwe amavutika kutembenuza folic acid.
Zotsatira za m'badwo wachinayi wa folic acid (5-MTHF) ndizosowa komanso zofatsa, koma ndikofunikira kudziwa zomwe zingachitike:
Zotsatira zoyipa:Monga chowonjezera chilichonse kapena mankhwala, matupi awo sagwirizana ndi zotheka.Zizindikiro zake zingaphatikizepo zotupa, kuyabwa, kutupa, chizungulire, kapena kupuma movutikira.Ngati mukukumana ndi chimodzi mwa zizindikirozi, pitani kuchipatala mwamsanga.
Mavuto am'mimba:Anthu ena amatha kukhala ndi vuto la m'mimba, monga nseru, kutupa, mpweya, kapena kutsekula m'mimba.Zizindikirozi nthawi zambiri zimakhala zosakhalitsa ndipo zimachepa pamene thupi likusintha kuti likhale lowonjezera.
Kuyanjana ndi mankhwala:5-MTHF imatha kuyanjana ndi mankhwala ena, kuphatikiza mankhwala omwe amagwiritsidwa ntchito pochiza khansa, anticonvulsants, methotrexate, ndi maantibayotiki ena.Ndikofunika kulankhula ndi wothandizira zaumoyo wanu ngati mukumwa mankhwala kuti muwonetsetse kuti palibe kugwirizana komwe kungachitike.
Overdose kapena kuchuluka kwa folate:Ngakhale ndizosowa, kudya kwambiri kwa folate (kuphatikiza 5-MTHF) kumatha kubweretsa kuchuluka kwa magazi m'magazi.Izi zitha kubisa zizindikiro za kuchepa kwa vitamini B12 ndikusokoneza kuzindikira ndi kuchiza matenda ena.Ndikofunika kutsatira mlingo wovomerezeka ndikuwonana ndi akatswiri azachipatala kuti akuthandizeni.
Zoganizira zina:Amayi oyembekezera kapena omwe akukonzekera kutenga pakati ayenera kukambirana ndi azaumoyo asanamwe mlingo wokulirapo wa 5-MTHF, chifukwa kudya kwambiri kwa folate kumatha kubisa zizindikiro za kusowa kwa vitamini B12, komwe ndikofunikira pakukula kwa neural chubu mwa mwana wosabadwayo.
Monga momwe zilili ndi zakudya zilizonse zowonjezera kapena mankhwala, ndikofunikira kukambirana za kagwiritsidwe ntchito ka folic acid (5-MTHF) ndi achipatala, makamaka ngati muli ndi vuto linalake kapena mukumwa mankhwala ena.Atha kukupatsani upangiri payekhapayekha malinga ndi zosowa zanu zenizeni ndikuthandizira kuyang'anira zovuta zilizonse zomwe zingachitike.
Folic acid ya m'badwo wachinai, yomwe imadziwikanso kuti 5-methyltetrahydrofolate (5-MTHF), ndi mtundu wa folate womwe umakhala wosavuta kutengeka ndikugwiritsidwa ntchito ndi thupi poyerekeza ndi zakudya zamtundu wa folic acid.Nawa maphunziro asayansi omwe amathandizira kugwira ntchito kwake:
Kuwonjezeka kwa bioavailability:5-MTHF yawonetsedwa kuti ili ndi bioavailability yayikulu kuposa folic acid.Kafukufuku wofalitsidwa mu American Journal of Clinical Nutrition anayerekezera bioavailability wa folic acid ndi 5-MTHF mwa amayi athanzi.Zinapeza kuti 5-MTHF idatengeka mwachangu ndikupangitsa kuti ma folate achuluke m'maselo ofiira amagazi.
Kusintha kwa folate:Kafukufuku wambiri awonetsa kuti kuwonjezera pa 5-MTHF kumatha kukulitsa milingo ya folate yamagazi.Mu mayeso oyendetsedwa mwachisawawa omwe adasindikizidwa mu Journal of Nutrition, ofufuza adayerekeza zotsatira za 5-MTHF ndi folic acid supplementation pamtundu wa folate mwa amayi athanzi.Adapeza kuti 5-MTHF inali yothandiza kwambiri pakuwonjezera ma cell ofiira a folate kuposa folic acid.
Kuchulukitsa kwa folic acid metabolism: +5-MTHF yawonetsedwa kuti imadutsa njira za enzymatic zomwe zimafunikira kuti folic acid activation ndi kutenga nawo mbali mwachindunji mu cell folic acid metabolism.Kafukufuku wofalitsidwa mu Journal of Nutrition and Metabolism adawonetsa kuti 5-MTHF supplementation imathandizira intracellular folate metabolism mwa anthu omwe ali ndi mitundu yosiyanasiyana ya ma enzyme omwe amakhudzidwa ndi kuyambitsa kwa folic acid.
Miyezo ya homocysteine yachepetsedwa:Kuchuluka kwa homocysteine, amino acid m'magazi, kumalumikizidwa ndi chiopsezo chowonjezeka cha matenda amtima.Kafukufuku wasonyeza kuti 5-MTHF supplementation imatha kuchepetsa milingo ya homocysteine.Meta-analysis yofalitsidwa mu Journal of the American College of Nutrition inasanthula mayesero 29 olamulidwa mwachisawawa ndipo adatsimikiza kuti 5-MTHF supplementation inali yothandiza kwambiri kuposa folic acid pochepetsa milingo ya homocysteine.
Ndikofunikira kuzindikira kuti mayankho amunthu pazowonjezera zowonjezera amatha kukhala osiyanasiyana, ndipo mphamvu ya 5-MTHF ingadalire zinthu monga kusiyanasiyana kwa ma genetic mu ma enzymes a folate metabolism komanso kudya kwathunthu.Nthawi zonse tikulimbikitsidwa kukaonana ndi azachipatala kuti mupeze upangiri wamunthu payekhapayekha pazakudya komanso kukambirana zovuta zilizonse zokhudzana ndi thanzi lanu.
