Calcium ya Methyltetrahydrofolate Yoyera (5MTHF-Ca)
Methyltetrahydrofolate Yoyera Calcium (5-MTHF-Ca) ndi mtundu wa folate womwe umapezeka kwambiri m'thupi ndipo ungagwiritsidwe ntchito mosavuta ndi thupi. Ndi mchere wa calcium wa methyltetrahydrofolate, womwe ndi mtundu wa folate womwe umagwira ntchito m'thupi. Folate ndi vitamini B wofunikira womwe umagwira ntchito yofunika kwambiri m'maselo osiyanasiyana, kuphatikizapo kupanga DNA, kupanga maselo ofiira amagazi, komanso kugwira ntchito kwa mitsempha.
MTHF-Ca nthawi zambiri imagwiritsidwa ntchito ngati chowonjezera pazakudya kuti chithandizire kuchuluka kwa folate mwa anthu omwe angakhale ndi vuto logwiritsa ntchito folic acid yopangidwa ndi thupi yomwe imapezeka muzakudya zolimbitsa thupi komanso zowonjezera. Ndi yothandiza makamaka kwa anthu omwe ali ndi majini osiyanasiyana omwe angasokoneze kagayidwe ka folate.
Kuwonjezera MTHF-Ca kungathandize kuthandizira thanzi lonse ndi thanzi labwino, makamaka m'magawo monga thanzi la mtima, kukula kwa machubu a mitsempha panthawi ya mimba, ntchito ya ubongo, komanso kusintha momwe munthu akumvera. Ndikofunikira kudziwa kuti MTHF-Ca iyenera kugwiritsidwa ntchito motsogozedwa ndi katswiri wazachipatala, makamaka kwa anthu omwe ali ndi matenda enaake kapena omwe akumwa mankhwala enaake.
| Dzina la chinthu： | L-5-Methyltetrahydrofolate calcium |
| Mafanizo ofanana： | 6S-5-Methyltetrahydrofolate calcium; Calcium L-5-Methyltetrahydrofolate; Levomefolate calcium |
| Fomula ya Maselo: | C20H23CaN7O6 |
| Kulemera kwa Maselo: | 497.52 |
| Nambala ya CAS: | 151533-22-1 |
| Zomwe zili: | ≥ 95.00% ndi HPLC |
| Maonekedwe: | Ufa wa kristalo woyera mpaka wachikasu wopepuka |
| Dziko lakochokera: | China |
| Phukusi: | 20kg/ng'oma |
| Nthawi yogwiritsira ntchito: | Miyezi 24 |
| Malo Osungira: | Sungani pamalo ozizira komanso ouma. |
| Zinthu | Mafotokozedwe | Zotsatira |
| Maonekedwe | Ufa woyera kapena wopanda mtundu woyera | Tsimikizirani |
| Kudziwika | Zabwino | Tsimikizirani |
| Kalisiyamu | 7.0% - 8.5% | 8.4% |
| D-5-Methylfolate | ≤1.0 | Sizinapezeke |
| Zotsalira pa kuyatsa | ≤0.5% | 0.01% |
| Madzi | ≤17.0% | 13.5% |
| Kuyesa (HPLC) | 95.0% -102.0% | 99.5% |
| Phulusa | ≤0.1% | 0.05% |
| Chitsulo Cholemera | ≤20 ppm | Tsimikizirani |
| Chiwerengero Chonse cha Ma Plate | ≤1000cfu/g | Woyenerera |
| Yisiti & Nkhungu | ≤100cfu/g | Woyenerera |
| E.coil | Zoyipa | Zoyipa |
| Salmonella | Zoyipa | Zoyipa |
Kupezeka kwa bioavailability kwambiri:MTHF-Ca ndi mtundu wa folate womwe umapezeka kwambiri m'thupi, zomwe zikutanthauza kuti ukhoza kuyamwa mosavuta ndikugwiritsidwa ntchito ndi thupi. Izi ndizofunikira chifukwa anthu ena angavutike kusintha folic acid yopangidwa kukhala yogwira ntchito.
Fomu yogwira ntchito ya folate:MTHF-Ca ndi mtundu wogwira ntchito wa folate, wotchedwa methyltetrahydrofolate. Mtundu uwu umagwiritsidwa ntchito mosavuta ndi thupi ndipo sufuna njira zina zowonjezera zosinthira.
Mchere wa Kalisiyumu:MTHF-Ca ndi mchere wa calcium, zomwe zikutanthauza kuti umagwirizanitsidwa ndi calcium. Izi zimapereka phindu lowonjezera la calcium pamodzi ndi folate support. Calcium ndi yofunika kwambiri pa thanzi la mafupa, ntchito ya minofu, kufalitsa mitsempha, ndi ntchito zina za thupi.
Oyenera anthu omwe ali ndi majini osiyanasiyana:MTHF-Ca ndi yothandiza kwambiri kwa anthu omwe ali ndi kusintha kwa majini komwe kungasokoneze kagayidwe ka folate. Kusintha kwa majini kumeneku kungakhudze mphamvu ya thupi yosinthira folic acid kukhala yogwira ntchito, zomwe zimapangitsa kuti kuwonjezera ndi folate yogwira ntchito kukhale kofunikira.
Zimathandizira mbali zosiyanasiyana za thanzi:Kuonjezera MTHF-Ca kungathandize thanzi lonse komanso thanzi labwino. Ndikothandiza makamaka pa thanzi la mtima, kukula kwa machubu a mitsempha panthawi ya mimba, kugwira ntchito bwino kwa ubongo, komanso kusintha momwe munthu akumvera.
Pure Methyltetrahydrofolate Calcium (MTHF-Ca) imapereka maubwino angapo paumoyo:
Chithandizo cha metabolism ya folic acid:MTHF-Ca ndi mtundu wa folate womwe umapezeka kwambiri m'thupi ndipo umagwira ntchito bwino. Umathandiza kuthandizira kagayidwe ka folate m'thupi, komwe ndikofunikira pakupanga DNA, kupanga maselo ofiira a magazi, komanso kugwira ntchito kwa maselo onse.
Thanzi la mtima:Kuchuluka kwa folate m'thupi ndikofunikira kwambiri pa thanzi la mtima. Kuonjezera MTHF-Ca kungathandize kuchepetsa kuchuluka kwa homocysteine, amino acid yomwe, ikakwezedwa, imagwirizanitsidwa ndi chiopsezo chowonjezeka cha matenda a mtima.
Chithandizo cha mimba:MTHF-Ca ndi yofunika kwambiri panthawi ya mimba, chifukwa imathandiza kupewa zolakwika za neural tube m'makanda omwe akukula. Azimayi a msinkhu wobereka amalangizidwa kuti azionetsetsa kuti ali ndi folate yokwanira, makamaka kumayambiriro kwa mimba.
Kulamulira maganizo:Folate imagwira ntchito yofunika kwambiri pakupanga ma neurotransmitter. Kuchuluka kwa folate komwe kumathandizira kupanga serotonin, dopamine, ndi norepinephrine, zomwe ndizofunikira kwambiri pakulamulira malingaliro. Kuonjezera MTHF-Ca kungakhale kothandiza kwa anthu omwe ali ndi matenda a maganizo, monga kuvutika maganizo.
Ntchito yozindikira:Folate ndi yofunika kwambiri pakugwira ntchito bwino kwa ubongo komanso thanzi la ubongo. Kuonjezera MTHF-Ca kungathandize kukumbukira, kuyang'ana kwambiri, komanso kugwira ntchito bwino kwa ubongo, makamaka kwa okalamba.
Thandizo la zakudya:Kuonjezera MTHF-Ca kungakhale kothandiza kwa anthu omwe ali ndi majini osiyanasiyana omwe amakhudza kagayidwe ka folate. Anthuwa akhoza kukhala ndi vuto losintha folic acid yopangidwa kukhala yogwira ntchito. MTHF-Ca imapereka mawonekedwe ogwira ntchito a folate mwachindunji, kupewa mavuto aliwonse osintha.
Zakudya zopatsa thanzi komanso zowonjezera zakudya:MTHF-Ca imagwiritsidwa ntchito kwambiri ngati chosakaniza chofunikira kwambiri mu zakudya zowonjezera komanso zakudya zopatsa thanzi. Imapereka mtundu wa folate womwe umapezeka kwambiri m'thupi, womwe umapereka maubwino ambiri azaumoyo, monga tafotokozera kale.
Kulimbitsa chakudya ndi zakumwa:MTHF-Ca ikhoza kuikidwa mu zakudya ndi zakumwa kuti iwonjezere folate. Izi ndizofunikira kwambiri pazinthu zomwe zimasamalira anthu omwe ali ndi vuto la folate kapena omwe amafunikira folate yambiri, monga amayi apakati kapena anthu omwe ali ndi matenda enaake.
Mankhwala opangira mankhwala:MTHF-Ca ingagwiritsidwe ntchito ngati mankhwala ochizira matenda enaake okhudzana ndi kusowa kwa folate kapena kusokonezeka kwa kagayidwe ka folate m'thupi, monga kuchepa kwa magazi m'thupi kapena matenda enaake a majini.
Kusamalira thupi ndi zodzoladzola:Nthawi zina MTHF-Ca imaphatikizidwa mu zinthu zosamalira thupi komanso zodzoladzola chifukwa cha ubwino wake pa thanzi la khungu. Folate imagwira ntchito m'maselo osiyanasiyana a khungu ndipo ingathandize pa thanzi lake lonse komanso mawonekedwe ake.
Chakudya cha ziweto:MTHF-Ca ingagwiritsidwenso ntchito mu chakudya cha ziweto kuti iwonjezere folate ku ziweto. Izi ndizofunikira kwambiri makamaka ku mafakitale a ziweto ndi nkhuku, komwe kuonetsetsa kuti chakudya chokwanira chikukula bwino komanso kukhala ndi thanzi labwino ndikofunikira.
Magawo ogwiritsira ntchito awa akuwonetsa kusinthasintha kwa MTHF-Ca ndi momwe ingagwiritsidwire ntchito m'mafakitale osiyanasiyana pothana ndi mavuto okhudzana ndi thanzi komanso zosowa za zakudya. Komabe, ndikofunikira kutsatira malangizo oyenera a mlingo ndikufunsana ndi akatswiri mukamagwiritsa ntchito MTHF-Ca mu mankhwala kapena mankhwala aliwonse.
Kupeza zinthu zopangira:Njirayi imayamba ndi kupeza zinthu zopangira zapamwamba kwambiri. Zinthu zofunika kwambiri popanga MTHF-Ca ndi folic acid ndi mchere wa calcium.
Kusintha kwa folic acid kukhala 5,10-Methylenetetrahydrofolate (5,10-MTHF):Folic acid imasinthidwa kukhala 5,10-MTHF kudzera mu njira yochepetsera. Gawoli nthawi zambiri limaphatikizapo kugwiritsa ntchito zinthu zochepetsera monga sodium borohydride kapena zinthu zina zoyenera zochepetsera.
Kusintha kwa 5,10-MTHF kukhala MTHF-Ca:5,10-MTHF imaphatikizidwanso ndi mchere woyenera wa calcium, monga calcium hydroxide kapena calcium carbonate, kuti ipange Methyltetrahydrofolate Calcium (MTHF-Ca). Njirayi imaphatikizapo kusakaniza ma reactants ndikulola kuti achitepo kanthu pansi pa mikhalidwe yolamulidwa, kuphatikizapo kutentha, pH, ndi nthawi yochitapo kanthu.
Kuyeretsa ndi kusefa:Pambuyo pa yankho, yankho la MTHF-Ca limadutsa njira zoyeretsera monga kusefa, kugawa mphamvu, kapena njira zina zolekanitsira kuti zichotse zodetsa ndi zinthu zina zomwe zingakhale zitapangidwa panthawi ya yankho.
Kuumitsa ndi kulimbitsa:Kenako yankho la MTHF-Ca loyeretsedwa limakonzedwanso kuti lichotse chinyezi chochulukirapo ndikulimbitsa chinthu chomaliza. Izi zitha kuchitika kudzera mu njira monga kuumitsa ndi kupopera kapena kuumitsa mufiriji, kutengera mtundu wa chinthu chomwe mukufuna.
Kuwongolera khalidwe ndi kuyesa:Chogulitsa chomaliza cha MTHF-Ca chimayesedwa mosamala kwambiri kuti chitsimikizire kuti chili choyera, chokhazikika, komanso chotsatira miyezo yodziwika bwino. Izi zitha kuphatikizapo kuyesa zodetsa, mphamvu, ndi zina zofunikira.
Kulongedza ndi kusungira:MTHF-Ca imapakidwa m'mabotolo oyenera, kuonetsetsa kuti zilembo zake ndi malo osungiramo zinthu zili bwino kuti zisunge bwino komanso kukhazikika. Nthawi zambiri imasungidwa pamalo ouma, ozizira, kutali ndi dzuwa lachindunji.
Kusunga: Sungani pamalo ozizira, ouma, komanso oyera, Tetezani ku chinyezi ndi kuwala kolunjika.
Phukusi Lochuluka: 25kg/ng'oma.
Nthawi Yotsogolera: Masiku 7 mutatha kuyitanitsa.
Moyo wa Shelf: Zaka ziwiri.
Ndemanga: Ma specifications opangidwa mwamakonda amathanso kukwaniritsidwa.
20kg/thumba 500kg/mphasa
Ma CD olimbikitsidwa
Chitetezo cha katundu
Express
Zolemera zosakwana 100kg, masiku 3-5
Utumiki wosavuta kutenga katundu pakhomo ndi khomo
Panyanja
Kupitirira 300kg, Pafupifupi masiku 30
Pakufunika katswiri wopereka chilolezo kuchokera ku doko kupita ku doko
Ndi Ndege
100kg-1000kg, Masiku 5-7
Pakufunika katswiri wopereka chithandizo kuchokera ku eyapoti kupita ku eyapoti
Calcium ya Methyltetrahydrofolate Yoyera (5-MTHF-Ca)ali ndi satifiketi ya ISO, satifiketi ya HALAL, ndi satifiketi ya KOSHER.
Kusiyana pakati pa m'badwo wachinayi wa folic acid (5-MTHF) ndi folic acid yachikhalidwe kuli mu kapangidwe ka mankhwala awo komanso kupezeka kwawo m'thupi.
Kapangidwe ka mankhwala:Folic acid yachikhalidwe ndi mtundu wa folate wopangidwa womwe umafunika kusinthidwa kangapo m'thupi usanagwiritsidwe ntchito. Kumbali inayi, folic acid ya m'badwo wachinayi, yomwe imadziwikanso kuti 5-MTHF kapena Methyltetrahydrofolate, ndi mtundu wa folate womwe umagwira ntchito, womwe umapezeka m'thupi ndipo sufuna kusinthidwa.
Kupezeka kwa zinthu zachilengedwe:Folic acid yachikhalidwe iyenera kusinthidwa kukhala 5-MTHF, kudzera mu zochita za enzyme m'thupi. Njira yosinthira iyi imasiyana pakati pa anthu ndipo imatha kukhudzidwa ndi kusintha kwa majini kapena zinthu zina. Mosiyana ndi zimenezi, 5-MTHF ili kale mu umunthu wake, zomwe zimapangitsa kuti igwiritsidwe ntchito mosavuta m'maselo.
Kuyamwa ndi kugwiritsa ntchito:Kumwa folic acid yachikhalidwe kumachitika m'matumbo ang'onoang'ono, komwe amafunika kusinthidwa kukhala mawonekedwe ogwirira ntchito ndi enzyme dihydrofolate reductase (DHFR). Komabe, njira yosinthira iyi siigwira ntchito bwino kwa anthu ena, zomwe zimapangitsa kuti bioavailability ikhale yochepa. 5-MTHF, yomwe ndi mawonekedwe ogwirira ntchito, imayamwa mosavuta ndikugwiritsidwa ntchito ndi thupi, kupitilira njira yosinthira. Izi zimapangitsa kuti ikhale njira yabwino kwambiri kwa anthu omwe ali ndi majini osiyanasiyana kapena matenda omwe amakhudza kagayidwe ka folate.
Kulimbitsa thupi kwa anthu ena:Chifukwa cha kusiyana kwa kuyamwa ndi kugwiritsa ntchito, 5-MTHF imaonedwa kuti ndi yoyenera kwambiri kwa anthu omwe ali ndi majini osiyanasiyana, monga kusintha kwa majini a MTHFR, komwe kungasokoneze kusintha kwa folic acid kukhala mawonekedwe ake ogwira ntchito. Kwa anthu awa, kugwiritsa ntchito 5-MTHF mwachindunji kungatsimikizire kuchuluka kwa folate m'thupi ndikuthandizira ntchito zosiyanasiyana zamoyo.
Zowonjezera:Folic acid yachikhalidwe imapezeka kwambiri mu zakudya zowonjezera, zakudya zolimbitsa thupi, ndi zakudya zokonzedwa, chifukwa ndi yokhazikika komanso yotsika mtengo kupanga. Komabe, pali kupezeka kwakukulu kwa zowonjezera 5-MTHF zomwe zimapereka mawonekedwe ogwira ntchito mwachindunji, zomwe zingakhale zothandiza kwa anthu omwe ali ndi vuto losintha folic acid.
Zotsatira zoyipa za folic acid ya m'badwo wachinayi (5-MTHF) nthawi zambiri zimakhala zochepa komanso zochepa, koma ndikofunikira kudziwa zomwe zingachitike:
Matenda a ziwengo:Monga mankhwala ena aliwonse owonjezera kapena mankhwala, zotsatirapo za ziwengo zimatha kuchitika. Zizindikiro zake zitha kukhala ziphuphu, kuyabwa, kutupa, chizungulire, kapena kupuma movutikira. Ngati mukukumana ndi zizindikiro izi, pitani kuchipatala mwachangu.
Mavuto a m'mimba:Anthu ena amatha kukhala ndi mavuto a m'mimba, monga nseru, kudzimbidwa, mpweya, kapena kutsegula m'mimba. Zizindikirozi nthawi zambiri zimakhala zakanthawi ndipo zimatha thupi likayamba kuzolowera chakudya chowonjezera.
Kuyanjana ndi mankhwala:5-MTHF ingagwirizane ndi mankhwala ena, kuphatikizapo mankhwala omwe amagwiritsidwa ntchito pochiza khansa, mankhwala oletsa kugwedezeka, methotrexate, ndi maantibayotiki ena. Ndikofunikira kulankhula ndi dokotala wanu ngati mukumwa mankhwala aliwonse kuti muwonetsetse kuti palibe kuyanjana komwe kungachitike.
Kuchuluka kwa folate kapena kuchuluka kwa folate m'thupi:Ngakhale kuti kudya folate mopitirira muyeso (kuphatikizapo 5-MTHF) kungayambitse kuchuluka kwa folate m'magazi. Izi zitha kubisa zizindikiro za kusowa kwa vitamini B12 ndikukhudza kuzindikira ndi kuchiza matenda ena. Ndikofunikira kutsatira mlingo woyenera ndikufunsa katswiri wazachipatala kuti akuthandizeni.
Zinthu zina zofunika kuziganizira:Amayi oyembekezera kapena omwe akukonzekera kutenga pakati ayenera kulankhula ndi dokotala wawo asanamwe 5-MTHF yambiri, chifukwa kudya kwambiri folate kungabise zizindikiro za kusowa kwa vitamini B12, komwe ndikofunikira kwambiri pakukula kwa minyewa ya mwana wosabadwayo.
Monga momwe zimakhalira ndi zakudya zina zowonjezera kapena mankhwala, ndikofunikira kukambirana ndi dokotala za kugwiritsa ntchito Four-generation folic acid (5-MTHF), makamaka ngati muli ndi matenda enaake kapena mukumwa mankhwala ena. Akhoza kukupatsani upangiri payekhapayekha kutengera zosowa zanu ndikuthandizira kuyang'anira zotsatirapo zilizonse zomwe zingachitike.
Folic acid ya m'badwo wachinayi, yomwe imadziwikanso kuti 5-methyltetrahydrofolate (5-MTHF), ndi mtundu wa folate womwe umagwira ntchito m'thupi ndipo umayamwa mosavuta ndikugwiritsidwa ntchito ndi thupi poyerekeza ndi folic acid yachikhalidwe. Nazi maphunziro ena asayansi omwe amathandizira kuti izi zigwire ntchito:
Kuwonjezeka kwa bioavailability:Kafukufuku wofalitsidwa mu American Journal of Clinical Nutrition anayerekezera kupezeka kwa folic acid ndi 5-MTHF mwa akazi athanzi. Anapeza kuti 5-MTHF imayamwa mwachangu ndipo izi zinapangitsa kuti maselo ofiira a m'magazi akhale ndi folate yambiri.
Mkhalidwe wabwino wa folate:Kafukufuku wambiri wasonyeza kuti kuwonjezera 5-MTHF kungathandize kukweza kuchuluka kwa folate m'magazi. Mu kafukufuku wolamulidwa mwachisawawa wofalitsidwa mu Journal of Nutrition, ofufuza anayerekeza zotsatira za 5-MTHF ndi folic acid pa thanzi la amayi athanzi. Anapeza kuti 5-MTHF inali yothandiza kwambiri pakuwonjezera kuchuluka kwa folate m'magazi kuposa folic acid.
Kuwonjezeka kwa kagayidwe ka folic acid m'thupi:Kafukufuku wofalitsidwa mu Journal of Nutrition and Metabolism wasonyeza kuti 5-MTHF imadutsa njira zomwe zimafunika kuti folic acid iyambe kugwira ntchito komanso kuti igwire ntchito mwachindunji mu metabolism ya folic acid m'maselo. Kafukufuku wofalitsidwa mu Journal of Nutrition and Metabolism adawonetsa kuti kuwonjezera 5-MTHF kumathandizira kagayidwe ka folate m'maselo mwa anthu omwe ali ndi majini osiyanasiyana mu ma enzyme omwe amagwira ntchito mu metabolism ya folic acid.
Kuchepa kwa homocysteine m'magazi:Kuchuluka kwa homocysteine, amino acid m'magazi, kumagwirizanitsidwa ndi chiopsezo chowonjezeka cha matenda a mtima. Kafukufuku wasonyeza kuti kuwonjezera 5-MTHF kungachepetse bwino kuchuluka kwa homocysteine. Kusanthula kwa meta komwe kunafalitsidwa mu Journal of the American College of Nutrition kunasanthula mayesero 29 olamulidwa mwachisawawa ndipo kunapeza kuti kuwonjezera 5-MTHF kunali kothandiza kwambiri kuposa folic acid pochepetsa kuchuluka kwa homocysteine.
Ndikofunikira kudziwa kuti mayankho a munthu aliyense pa chithandizo chamankhwala amatha kusiyana, ndipo kugwira ntchito kwa 5-MTHF kungadalire zinthu monga kusintha kwa majini mu ma enzymes a folate metabolism ndi kudya zakudya zonse. Nthawi zonse ndi bwino kufunsa dokotala kuti akupatseni upangiri wokhudza chithandizo chamankhwala komanso kukambirana za mavuto enaake azaumoyo.
