Theaflavins (TFs)ndiThearubigins (TRs)Ndi magulu awiri osiyana a mankhwala a polyphenolic omwe amapezeka mu tiyi wakuda, iliyonse ili ndi mankhwala apadera komanso makhalidwe ake. Kumvetsetsa kusiyana pakati pa mankhwala awa ndikofunikira kuti timvetsetse zomwe amapereka pa makhalidwe ndi ubwino wa tiyi wakuda pa thanzi. Nkhaniyi ikufuna kufotokoza mwatsatanetsatane kusiyana pakati pa Theaflavins ndi Thearubigins, mothandizidwa ndi umboni wochokera ku kafukufuku woyenera.
Ma theaflavins ndi thearubigins onse ndi ma flavonoids omwe amathandizira ku mtundu, kukoma, ndi thupi la tiyi.Theaflavins ndi lalanje kapena wofiira, ndipo thearubigins ndi wofiira-bulauniMa flavonoids ndi ma flavonoid oyamba kutuluka panthawi ya okosijeni, pomwe ma thearubigins amatuluka pambuyo pake. Ma theaflavins amathandizira kulimba kwa tiyi, kuwala, ndi kunyezimira, pomwe ma thearubigins amathandizira kulimba kwake komanso kumva mkamwa.
Ma theaflavin ndi gulu la mankhwala a polyphenolic omwe amathandizira ku mtundu, kukoma, komanso thanzi la tiyi wakuda. Amapangidwa kudzera mu oxidative dimerization ya ma catechins panthawi yophika masamba a tiyi. Ma theaflavin amadziwika chifukwa cha antioxidant yawo komanso anti-inflammatory, zomwe zalumikizidwa ndi maubwino osiyanasiyana azaumoyo, kuphatikiza chitetezo cha mtima, mphamvu zotsutsana ndi khansa, komanso zotsatira zomwe zingachitike poletsa ukalamba.
Mbali inayi,ThearubiginsNdi mankhwala akuluakulu a polyphenolic omwe amachokera ku okosijeni wa ma polyphenols a tiyi panthawi yophika masamba a tiyi. Ndi omwe amachititsa mtundu wofiira kwambiri komanso kukoma kwapadera kwa tiyi wakuda. Thearubigins akhala akugwiritsidwa ntchito ngati antioxidant, anti-inflammatory, komanso anti-pakhungu, zomwe zimapangitsa kuti azikondedwa kwambiri pankhani yoletsa ukalamba komanso kusamalira khungu.
Malinga ndi mankhwala, ma Theaflavin ndi osiyana ndi ma Thearubigins malinga ndi kapangidwe ka mamolekyu awo ndi kapangidwe kawo. Ma Theaflavin ndi ma dimeric compounds, zomwe zikutanthauza kuti kuphatikiza kwa mayunitsi awiri ang'onoang'ono kumawapanga, pomwe ma Thearubigins ndi ma polymeric compounds akuluakulu omwe amachokera ku polymerization ya ma flavonoids osiyanasiyana panthawi yophika tiyi. Kusiyana kwa kapangidwe kameneka kumathandizira pa ntchito zawo zosiyanasiyana zamoyo komanso zotsatira zake pa thanzi.
| Theaflavins | Thearubigins | |
| Mtundu | Lalanje kapena wofiira | Wofiira-bulauni |
| Zopereka ku tiyi | Kulimba, kuwala, ndi kunyezimira | Mphamvu ndi kumveka pakamwa |
| Kapangidwe ka mankhwala | Yofotokozedwa bwino | Zosiyana komanso zosadziwika |
| Kuchuluka kwa kulemera kouma mu tiyi wakuda | 1–6% | 10–20% |
Ma theaflavins ndi gulu lalikulu la mankhwala omwe amagwiritsidwa ntchito poyesa ubwino wa tiyi wakuda. Chiŵerengero cha theaflavins ndi thearubigins (TF:TR) chiyenera kukhala 1:10 mpaka 1:12 pa tiyi wakuda wapamwamba. Nthawi yophika ndi chinthu chofunikira kwambiri kuti chiŵerengero cha TF:TR chikhalebe cholimba.
Ma Theaflavins ndi thearubigins ndi zinthu zapadera zomwe zimapangidwa kuchokera ku ma catechins panthawi ya enzyme oxidation ya tiyi popanga. Ma Theaflavins amapereka mtundu wa lalanje kapena lalanje wofiira ku tiyi ndipo amathandizira kumva bwino mkamwa komanso kupanga kirimu. Ndi mankhwala a dimeric omwe ali ndi mafupa a benzotropolone omwe amapangidwa kuchokera ku co-oxidation ya ma catechins osankhidwa. Kusungunuka kwa mphete ya B ya (−)-epigallocatechin kapena (−)-epigallocatechin gallate kumatsatiridwa ndi kutayika kwa CO2 ndi kusakanikirana nthawi imodzi ndi mphete ya B ya molekyulu ya (−)-epicatechin kapena (−)-epicatechin gallate (Chithunzi 12.2). Ma theaflavins anayi akuluakulu apezeka mu tiyi wakuda: theaflavin, theaflavin-3-monogallate, theaflavin-3′-monogallate, ndi theaflavin-3,3′-digallate. Kuphatikiza apo, ma stereoisomers ndi zotumphukira zawo zitha kupezeka. Posachedwapa, kupezeka kwa theaflavin trigallate ndi tetragallate mu tiyi wakuda kunanenedwa (Chen et al., 2012). Theaflavins amatha kuwonjezeredwa okosijeni. Mwina ndi omwe amayambitsa mapangidwe a polymeric thearubigins. Komabe, njira yochitira izi sinadziwike mpaka pano. Thearubigins ndi utoto wofiira-bulauni kapena wakuda-bulauni mu tiyi wakuda, zomwe zili mkati mwake zimapangitsa kuti 60% ya kulemera kouma kwa tiyi.
Ponena za ubwino wa thanzi, Theaflavins aphunziridwa kwambiri kuti angathandize kulimbitsa thanzi la mtima. Kafukufuku wasonyeza kuti Theaflavins angathandize kuchepetsa kuchuluka kwa cholesterol m'magazi, kukonza magwiridwe antchito a mitsempha yamagazi, komanso kukhala ndi mphamvu zotsutsana ndi kutupa, zomwe zonse zimathandiza pa thanzi la mtima. Kuphatikiza apo, Theaflavins awonetsa kuthekera koletsa kukula kwa maselo a khansa ndipo akhoza kukhala ndi mphamvu zotsutsana ndi matenda a shuga.
Kumbali inayi, Thearubigins yakhala ikugwiritsidwa ntchito pochiza ma antioxidants ndi kutupa, zomwe ndizofunikira kwambiri polimbana ndi kupsinjika kwa okosijeni ndi kutupa m'thupi. Makhalidwe amenewa angathandize kuti Thearubigins ikhale ndi mphamvu zoteteza kukalamba komanso khungu, zomwe zimapangitsa kuti azikondedwa kwambiri ndi anthu okalamba komanso kafukufuku wokhudzana ndi ukalamba.
Pomaliza, Theaflavins ndi Thearubigins ndi mankhwala apadera a polyphenolic omwe amapezeka mu tiyi wakuda, iliyonse ili ndi mankhwala apadera komanso ubwino wathanzi. Ngakhale kuti Theaflavins yagwirizanitsidwa ndi thanzi la mtima, mphamvu zotsutsana ndi khansa, komanso mphamvu zotsutsana ndi matenda a shuga, Thearubigins yagwirizanitsidwa ndi mphamvu zotsutsana ndi antioxidant, zotsutsana ndi kutupa, komanso zoteteza khungu, zomwe zimapangitsa kuti zikhale zosangalatsa kwambiri pa kafukufuku wotsutsana ndi ukalamba komanso chisamaliro cha khungu.
Maumboni:
Hamilton-Miller JM. Mphamvu zotsutsana ndi tizilombo toyambitsa matenda za tiyi (Camellia sinensis L.). Mankhwala Oletsa Tizilombo toyambitsa matenda Chemother. 1995;39(11):2375-2377.
Khan N, Mukhtar H. Tiyi ya polyphenols yolimbikitsa thanzi. Life Sci. 2007;81(7):519-533.
Mandel S, Youdim MB. Catechin polyphenols: kuwonongeka kwa mitsempha ndi kuteteza mitsempha m'matenda owonongeka ndi mitsempha. Free Radic Biol Med. 2004;37(3):304-17.
Jochmann N, Baumann G, Stangl V. Tiyi wobiriwira ndi matenda a mtima: kuchokera ku zolinga za molekyulu kupita ku thanzi la anthu. Curr Opin Clin Nutr Metab Care. 2008;11(6):758-765.
Nthawi yotumizira: Meyi-11-2024
