Nkhani - Kodi Makanda Angamwe Nervonic Acid?

I. Chiyambi

Makolo ambiri amadabwa ngati makanda angamwe nervonic acid. Musanayankhe funso ili, ndikofunikira kumvetsetsa komwe kumachokera nervonic acid. Popeza mkaka wa m'mawere uli ndi nervonic acid, wina angafunse ngati mkaka wa m'mawere nawonso suyenera kumwedwa. Koma kupatula mkaka wa m'mawere, kodi makanda osakwana zaka zitatu angamwe nervonic acid kuchokera kuzinthu zina?

II. Kodi Nervonic Acid ndi chiyani?

Asidi wa mitsempha, yomwe imadziwikanso kuti selacholeic acid, imatchedwa mwasayansi kuti cis-15-tetracosenoic acid. Ndi mtundu wa omega-9 monounsaturated fatty acid. Popeza idapezeka koyamba m'mitsempha yamagazi ya zoyamwitsa, nthawi zambiri imatchedwa nervonic acid.

Asidi ya Nervonic ndi gawo la nembanemba zamoyo, makamaka zomwe zimapezeka mu mawonekedwe a glycolipids ndi sphingomyelin mu white matter ya ubongo wa munthu, retina, umuna, ndi minofu ya mitsempha.

III. Ubwino wa Nervonic Acid

Dzina lakuti "nervonic acid" limasonyeza ntchito yake yaikulu: kupindulitsa dongosolo la mitsempha. Kuphatikiza apo, chifukwa cha kusakhuta kwake, limaperekanso ubwino wa mtima ndi mitsempha. Tiyeni tifufuze mozama:

Zimalimbikitsa Kukula kwa Ubongo

Kuyerekeza pakati pa makanda obadwa msanga ndi obadwa nthawi zonse kwasonyeza kuti makanda obadwa nthawi zonse amakhala ndi nervonic acid yambiri mu ubongo wa makanda obadwa nthawi zonse. Kafukufuku akusonyeza kuti nervonic acid ingakhudze kukula kwa mutu wa makanda.
Asidi ya Nervonic imayendetsa ntchito ya nembanemba ya maselo a muubongo, kupititsa patsogolo kutumiza uthenga pakati pa maselo a muubongo ndikuwonjezera ntchito ya calcium ion. Kafukufuku wa nyama akuchirikiza izi, akusonyeza kuti zowonjezera za asidi ya nervonic pakamwa zimatha kupititsa patsogolo kuphunzira ndi kukumbukira m'makoswe abwinobwino komanso omwe ali ndi vuto la kukumbukira. Chifukwa chake, akuganiziridwa kuti asidi ya nervonic ikhoza kukonza kukumbukira ndi kuzindikira kwa anthu.

Zimathandiza Kuyang'ana Kwambiri

Matenda a Attention Deficit Hyperactivity Disorder (ADHD) amadziwika ndi kusaganizira bwino, kusachita zinthu mopitirira muyeso, komanso kuchita zinthu mopitirira muyeso. ADHD ingayambitse kusachita bwino pa maphunziro, kusayanjana bwino ndi anzawo, komanso kusokonezeka kwa magwiridwe antchito a anthu. Kafukufuku wasonyeza kuti ana omwe ali ndi ADHD ali ndi milingo yochepa ya nervonic acid m'magazi awo poyerekeza ndi ana abwinobwino. Kafukufuku akusonyeza kuti kuwonjezera ndi nervonic acid yokwanira kungathandize ana kukhala ndi zizindikiro za ADHD komanso kukhala ndi chidwi chokhazikika.

Amachepetsa Chiwopsezo cha Matenda a Alzheimer's, Psychosis, ndi Depression

Kusanthula kwa okalamba 260 omwe ali ndi vuto la kuzindikira komanso ma serum fatty acid awo kunawonetsa kuchepa kwa chiopsezo cha matenda a Alzheimer's (AD) ndi kuchuluka kwa nervonic acid ndi DHA. Kuphatikiza apo, zoyeserera zawonetsa kuti mafuta a mbewu ya maple okhala ndi nervonic acid amatha kuyambitsa njira yolumikizirana ya BDNF/TrkB, kuwonjezera kufotokozera kwa mapuloteni a postsynaptic PSD95, GluA1, ndi NMDAR1, ndikuchepetsa kuchuluka kwa mRNA kwa zinthu zotupa monga IL-1β, TNFα, ndi IL-6, motero kuchepetsa kufooka kwa mitsempha ndikuwongolera kukumbukira mwa okalamba.
Kafukufuku wina wagwirizanitsa kuchepa kwa nervonic acid ndi zizindikiro za prodromal za psychosis ndi kuvutika maganizo. Kafukufuku akusonyeza kuti kuwonjezera mokwanira nervonic acid kungachepetse chiopsezo cha matenda a Alzheimer's, psychosis, ndi kuvutika maganizo.

Amalimbikitsa Kukonza Myelin

Kuyesera pa mbewa zomwe zinapatsidwa mafuta a mbewu ya maple okhala ndi nervonic acid kunawonetsa kuti mbewa izi zinatsala pang'ono kuchira kufika pamlingo wa gulu lolamulira. Kafukufuku wina wasonyeza kuti kuwonjezera zakudya ndi nervonic acid kungathandize kukhwima ndi kubwezeretsanso kwa oligodendrocytes.

Kuchepetsa Chiwopsezo cha Matenda a Mtima

Kafukufuku wapeza kuti nervonic acid imatha kuchepetsa chiopsezo cha sitiroko ya ischemic. Zifukwa zake ndi izi:
Kukonza ndi kuchotsa njira zolumikizirana za mitsempha muubongo zomwe zawonongeka
Kubwezeretsa ntchito ya mitsempha
Kulimbikitsa kusinthika kwa maselo a mitsempha
Kuletsa kukalamba kwa mitsempha ya ubongo
Kukonza ndi kubwezeretsa makoma okalamba, owonongeka, komanso olimba a dongosolo la mtima
Kusintha minofu ya khoma la mitsempha yamagazi
Kubwezeretsa kulimba ndi mphamvu ya mitsempha yamagazi

IV. Kodi makanda angamwe Nervonic Acid? Kodi ayenera kuyamba liti kuwonjezera mankhwala?

Yankho lake ndi losavuta kwenikweni. Tiyeni tione kuwunika kwa madipatimenti ovomerezeka a m'dziko ndi akunja, komanso malamulo oyenera okhudza chakudya.

1. Malamulo a FDA

Malinga ndi zikalata zovomerezeka za FDA, nervonic acid yochokera ku mankhwala ingagwiritsidwe ntchito ngati mankhwala.
Pochiza matenda monga isovaleric acidemia, mlingo wake ndi 200-300mg.

Komabe, FDA sinavomereze kuti nervonic acid kuchokera kuzinthu zina imagwiritsidwa ntchito mu mkaka wa ana. Malinga ndi malamulo a FDA, ngati chosakaniza chikugwiritsidwa ntchito mu mkaka wa ana, chiyenera kudziwika kuti ndi Chotetezeka (GRAS) ndi US FDA pa mkaka wa ana. Nervonic acid sichikukwaniritsa izi.

2. Malamulo a EU

EU sinawunikenso mwachindunji za nervonic acid, kotero palibe chidziwitso chofunikira chomwe chilipo.

3. Malamulo aku China

Kuyambira pa 22 Marichi, 2011, Unduna wa Zaumoyo udapereka chidziwitso cholengeza kuti mafuta a mbewu ya maple avomereza chilengezo chatsopano cha chakudya.

Pophatikiza malamulo ndi kufufuza kuchuluka kwa asidi wa nervonic mu mafuta a mbewu ya maple, zapezeka kuti mafuta a mbewu ya maple nthawi zambiri amakhala ndi asidi wa nervonic 3%-5%. Malinga ndi malamulo atsopano azakudya, kuchuluka kwa asidi wa nervonic tsiku lililonse ndi pafupifupi 150mg.
Monga tanenera kale, dzina la mankhwala la nervonic acid ndi cis-15-tetracosenoic acid. Mu 2017, National Health and Family Planning Commission idatulutsa chilengezo china chatsopano cha chakudya chokhudza mankhwala a nervonic acid ochokera ku mafuta a rapeseed.

Chilengezochi chinagogomezera makamaka kuti makanda sayenera kumwa zinthu zotere, ndipo ngati mankhwalawa akugwiritsa ntchito mankhwalawo mwachindunji, chizindikirocho chiyenera kusonyeza kuti sichoyenera makanda.

Kutengera malamulo omwe alipo, mosasamala kanthu kuti asidi wa nervonic amachokera ku mankhwala kapena chakudya, si woyenera makanda. Anthu ambiri angafunse kuti, "Koma ngati mkaka wa m'mawere uli nawo, bwanji sitingathe kuugwiritsa ntchito?" Izi zikuphatikizapo mbali ziwiri. Choyamba, pakadali pano pali kafukufuku wochepa wokhudza chitetezo cha asidi wa nervonic kwa makanda, ndipo sunagwiritsidwe ntchito kwambiri padziko lonse lapansi. Kafukufuku wowonjezera akufunika. Chachiwiri, ngati makanda amafunika kuwonjezera asidi wa nervonic ndi funso lomwe silinakwanire mokwanira. Pakadali pano palibe deta yokwanira yotsimikizira kuti makanda ali ndi vuto la nervonic acid. Chifukwa chake, kafukufuku wowonjezera akufunika kuti atsimikizire izi.

Chifukwa chake, kutengera malamulo ndi kuwunika komwe kukuchitika pano, tikulimbikitsidwa kuyamba kuwonjezera mankhwala a nervonic acid ali ndi zaka zitatu kapena kuposerapo. Makolo ambiri angamve bwino ngati awonjezera makanda osakwana zaka zitatu. Pazochitika zotere, kuwonjezera chakudya kumalimbikitsidwa.

Kuti tibwerezenso, palibe umboni wokwanira wotsimikizira kuti makanda amapatsidwa mankhwala a nervonic acid. Malinga ndi kafukufuku wa zachipatala komanso zakudya, palibe umboni wosonyeza kuti mankhwala owonjezera ndi ofunikira. Chifukwa chake, tikulimbikitsidwa kugwiritsa ntchito njira yoyenera popatsa makanda mankhwala a nervonic acid.

Ngakhale kholo lililonse limafuna mwana wanzeru, ndi bwino kuganizira kwambiri zakudya zopatsa thanzi komanso kukhala ndi nthawi yochulukirapo ndi mwana wanu, kukhala ndi moyo wabwino, komanso kulimbikitsa zochita zakunja. Zinthu zimenezi nthawi zambiri zimakhala zofunika kwambiri.